PDGF-AA Protein, Mouse, Recombinant

Name: PDGF-AA Protein, Mouse, Recombinant
Brand: TargetMol
SKU: TMPS-00114
Price: 119 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: Platelet-Derived Growth Factor-AA, PDGFAA, Osteosarcoma-derived Growth Factor, ODGF, Glioma-derived growth factor, GDGF) Copy Product Info

Synonyms: Platelet-Derived Growth Factor-AA, PDGFAA, Osteosarcoma-derived Growth Factor, ODGF, Glioma-derived growth factor, GDGF

Catalog No. TMPS-00114 Copy Product Info

PDGF-AA Protein, Mouse, Recombinant is expressed in E. coli. The accession number is P20033.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$119	-	In Stock
10 µg	$198	-	In Stock
20 µg	$282	-	In Stock
50 µg	$453	-	In Stock
100 µg	$745	-	In Stock
200 µg	$1,220	7-10 days	7-10 days
500 µg	$2,390	7-10 days	7-10 days
1 mg	$3,960	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:> 95% as determined by SDS-PAGE

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	ED 50 < 50.0 ng/ml, measured in a cell proliferation assay using 3T3 cells.
Description	PDGF-AA Protein, Mouse, Recombinant is expressed in E. coli. The accession number is P20033.
Species	Mouse
Expression System	E. coli
Tag	Tag Free
Accession Number	P20033
Construction	Ser87-Thr211
Protein Purity	> 95% as determined by SDS-PAGE
Endotoxin	< 0.2 EU/μg of protein as determined by the LAL method.
Formulation	Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	Platelet-Derived Growth Factor-AA, PDGFAA, Osteosarcoma-derived Growth Factor, ODGF, Glioma-derived growth factor, GDGF
Research Background	Platelet-Derived Growth Factor-AA (PDGF-AA) is one of five dimers (PDGF-AA, AB, BB, CC, and DD) formed by 4 different PDGF subunits. In chemical terms, platelet-derived growth factor is a dimeric glycoprotein composed of two A (-AA) or two B (-BB) chains or a combination of the two (-AB). The dimeric isoforms PDGFAA, AB and BB are differentially expressed in various cell types, and their effects are mediated through two distinct receptors termed α and β. Differences exist in isoform binding to each receptor. Ingeneral, PDGF isoforms are potent mitogens for connective tissue cells including dermal fibroblasts, glial cells, arterial smooth muscle cells and some epithelial andendothelial cells. In addition to its activity as a mitogen, PDGF is chemotactic for fibroblasts, smooth muscle cells, neutrophils and mononuclear cells. PDGF-AA plays a significant role in blood vessel formation (angiogenesis).

Chemical Properties

Molecular Weight

~28.7 kDa (Reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.