Complement C8 gamma Protein, Human, Recombinant (His)

Name: Complement C8 gamma Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPJ-00585
Rating: 4.5 (1 reviews)

(Synonyms: Complement component C8 γ chain, Complement component C8 gamma chain, C8G, C8 γ) Copy Product Info

Synonyms: Complement component C8 γ chain, Complement component C8 gamma chain, C8G, C8 γ

Catalog No. TMPJ-00585 Copy Product Info

Complement component C8 is a constituent of the membrane attack complex, C8 alpha, C8 beta and C8G. C8G is a secreted protein and comsists a disulfide-linked C8 alpha-gamma heterodimer and a non-covalently associated C8 beta chain. C8 alpha and C8 beta play an important role in complement-mediated bacterial killing together.C8 is involved in the formation of Membrane Attack Complex on bacterial cell membranes. C8 binds to the C5B-7 complex, forming the C5B-8 complex. C5-B8 binds C9 and acts as a catalyst in the polymerization of C9. The gamma subunit seems to be able to bind retinol. Patients lacking C8 are susceptible to certain bacterial infections.

Complement C8 gamma Protein, Human, Recombinant (His)

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Pack Size	Price	USA Stock	Global Stock
5 μg	$80	35 days	35 days
10 μg	$129	35 days	35 days
20 μg	$198	35 days	35 days
50 μg	$390	35 days	35 days
100 μg	$626	35 days	35 days
200 μg	$987	35 days	35 days
500 μg	$1,900	35 days	35 days
1 mg	$2,730	35 days	35 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity


Description	Complement component C8 is a constituent of the membrane attack complex, C8 alpha, C8 beta and C8G. C8G is a secreted protein and comsists a disulfide-linked C8 alpha-gamma heterodimer and a non-covalently associated C8 beta chain. C8 alpha and C8 beta play an important role in complement-mediated bacterial killing together.C8 is involved in the formation of Membrane Attack Complex on bacterial cell membranes. C8 binds to the C5B-7 complex, forming the C5B-8 complex. C5-B8 binds C9 and acts as a catalyst in the polymerization of C9. The gamma subunit seems to be able to bind retinol. Patients lacking C8 are susceptible to certain bacterial infections.
Species	Human
Expression System	E. coli
Tag	N-6xHis
Accession Number	AAI13627.1
Amino Acid	Gln21-Arg202
Construction	Gln21-Arg202
Protein Purity	Greater than 95% as determined by SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
Stability & Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	Proteins are shipped with blue ice.
Synonyms	Complement component C8 γ chain, Complement component C8 gamma chain, C8G, C8 γ
Research Background

Chemical Properties

Molecular Weight

22 KDa (reducing condition)

Storage & Solubility Information

Storage

Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Related Tags: Complement C8 gamma Protein, Human, Recombinant (His) chemical structure | Complement C8 gamma Protein, Human, Recombinant (His) molecular weight