Select your Country or Region

  • TargetMol | Compound LibraryArgentinaArgentina
  • TargetMol | Compound LibraryAustraliaAustralia
  • TargetMol | Compound LibraryAustriaAustria
  • TargetMol | Compound LibraryBelgiumBelgium
  • TargetMol | Compound LibraryBrazilBrazil
  • TargetMol | Compound LibraryBulgariaBulgaria
  • TargetMol | Compound LibraryCroatiaCroatia
  • TargetMol | Compound LibraryCyprusCyprus
  • TargetMol | Compound LibraryCzechCzech
  • TargetMol | Compound LibraryDenmarkDenmark
  • TargetMol | Compound LibraryEgyptEgypt
  • TargetMol | Compound LibraryEstoniaEstonia
  • TargetMol | Compound LibraryFinlandFinland
  • TargetMol | Compound LibraryFranceFrance
  • TargetMol | Compound LibraryGermanyGermany
  • TargetMol | Compound LibraryGreeceGreece
  • TargetMol | Compound LibraryHong KongHong Kong
  • TargetMol | Compound LibraryHungaryHungary
  • TargetMol | Compound LibraryIcelandIceland
  • TargetMol | Compound LibraryIndiaIndia
  • TargetMol | Compound LibraryIrelandIreland
  • TargetMol | Compound LibraryIsraelIsrael
  • TargetMol | Compound LibraryItalyItaly
  • TargetMol | Compound LibraryJapanJapan
  • TargetMol | Compound LibraryKoreaKorea
  • TargetMol | Compound LibraryLatviaLatvia
  • TargetMol | Compound LibraryLebanonLebanon
  • TargetMol | Compound LibraryMalaysiaMalaysia
  • TargetMol | Compound LibraryMaltaMalta
  • TargetMol | Compound LibraryMoroccoMorocco
  • TargetMol | Compound LibraryNetherlandsNetherlands
  • TargetMol | Compound LibraryNew ZealandNew Zealand
  • TargetMol | Compound LibraryNorwayNorway
  • TargetMol | Compound LibraryPolandPoland
  • TargetMol | Compound LibraryPortugalPortugal
  • TargetMol | Compound LibraryRomaniaRomania
  • TargetMol | Compound LibrarySingaporeSingapore
  • TargetMol | Compound LibrarySlovakiaSlovakia
  • TargetMol | Compound LibrarySloveniaSlovenia
  • TargetMol | Compound LibrarySpainSpain
  • TargetMol | Compound LibrarySwedenSweden
  • TargetMol | Compound LibrarySwitzerlandSwitzerland
  • TargetMol | Compound LibraryTaiwan,ChinaTaiwan,China
  • TargetMol | Compound LibraryThailandThailand
  • TargetMol | Compound LibraryTurkeyTurkey
  • TargetMol | Compound LibraryUnited KingdomUnited Kingdom
  • TargetMol | Compound LibraryUnited StatesUnited States
  • TargetMol | Compound LibraryOther CountriesOther Countries
Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
Filter
TargetMol | Tags GPCR/G Protein
TargetMol | Tags Neuroscience

Adrenergic Receptor

The adrenergic receptors or adrenoceptors are a class of G protein-coupled receptors that are targets of many catecholamines like norepinephrine (noradrenaline) and epinephrine (adrenaline) produced by the body, but also many medications like beta blockers, β2 agonists and α2 agonists, which are used to treat high blood pressure and asthma, for example.

  • Ritanserin
    T1675987051-43-2
    Ritanserin (R 55667) is a highly effective, relatively selective, long-acting antagonist of 5-HT2 receptor (IC50: 0.9 nM), less active on Histamine H1, Dopamine D2, Adrenergic α1, Adrenergic α2 receptors.
    • $34
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Hot
    TargetMol | Citations Cited
  • Bedoradrine sulfate
    T26760194785-31-4In house
    Bedoradrine sulfate (MN-221 sulfate) is a super-selective beta2 agonist for the treatment of asthma exacerbations and chronic obstructive pulmonary disease.
    • $762
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Hot
  • Bedoradrine
    T70047194785-19-8In house
    Bedoradrine free base is a novel, highly selective β2-adrenoceptor agonist for the treatment of asthma and chronic obstructive pulmonary disease (COPD).
    • $762
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Hot
  • CL 316243
    T10830138908-40-4In house
    CL316243 is a highly potent selective agonist of β3-adrenoceptor, with a EC50 of 3 nM. CL316243 is an effective stimulant of adipocyte lipolysis and increases brown adipose tissue thermogenesis and metabolic rate. CL316243 has the potential for the treatment obesity, diabetes and urge urinary incontinence.
    • $48
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Hot
  • AVN-101
    T266901061354-48-0
    AVN-101 is a potent 5-HT7 receptor antagonist.
    • $32
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Hot
  • Gemfibrozil
    T141525812-30-0
    Gemfibrozil (CI-719) interacts with peroxisome proliferator-activated receptors (PPARalpha) resulting in PPARalpha-mediated stimulation of fatty acid oxidation and an increase in lipoprotein lipase (LPL) synthesis. Gemfibrozil is a fibric acid derivative with hypolipidemic effects. This enhances triglyceride-rich lipoprotein clearance and reduces the expression of apolipoprotein C-III (apoC-III). The reduction in hepatic production of apoC-III result in the subsequent reduction of serum levels of very-low-density-lipoprotein cholesterol (VLDL-C). In addition, gemfibrozil-mediated PPARalpha stimulation of apoA-I and apoA-II expression results in an increase in high-density lipoprotein cholesterol (HDL-C).
    • $30
    In Stock
    Size
    QTY
  • Alfuzosin
    T2223281403-80-7
    Alfuzosin (SL 77499) is an orally available, competitive α1-adrenoceptor antagonist.Alfuzosin induces smooth muscle relaxation in the bladder neck and prostate.Alfuzosin has been used to study benign prostatic hypertrophy, lower urinary tract symptoms (LUTS), and ejaculatory dysfunction (EjD).
    • $40
    In Stock
    Size
    QTY
  • Terbutaline
    T881023031-25-6
    Terbutaline is a short-acting agonist of β2-adrenergic receptor (β2-AR) . It is an active metabolite of bambuterol
    • $36
    In Stock
    Size
    QTY
  • Indacaterol
    T2320312753-06-3
    Indacaterol (Onbrez; Arcapta) is a β2-Adrenergic Agonist. The mechanism of action of indacaterol is as an Adrenergic beta2-Agonist.
    • $43
    In Stock
    Size
    QTY
  • Ziprasidone hydrochloride monohydrate
    T0031138982-67-9
    Ziprasidone hydrochloride monohydrate (CP 88059) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of the antipsychotic activity.
    • $50
    In Stock
    Size
    QTY
  • Rauwolscine hydrochloride
    T44296211-32-1
    Rauwolscine hydrochloride (Isoyohimbine hydrochloride) , a natural alkaloid, is a specific and reversible α2-adrenergic receptor antagonist (Ki: 12 nM) [1]. It is a stereoisomer of yohimbine, which potently antagonizes both α1- and α2-adrenergic receptors [1]. Rauwolscine hydrochloride also acts as a receptor antagonist at the serotonin 5-HT2B receptor (Ki: 14.3 nM) and as a weak partial agonist at 5-HT1A (IC50: 1.3 μM) [3]. The α2-adrenergic receptor has diverse physiological functions and antagonists like rauwolscine have numerous applications, including the modulation of mood and behavior [5].
    • $50
    In Stock
    Size
    QTY
  • Dexmedetomidine hydrochloride
    T6466145108-58-3
    Dexmedetomidine hydrochloride (Precedex) is an imidazole derivative that is an agonist of the adrenergic alpha-2 receptor. It is closely-related to MEDETOMIDINE, which is the racemic form of this compound.
    • $35
    In Stock
    Size
    QTY
  • Mianserin hydrochloride
    T078321535-47-7
    Mianserin hydrochloride (Org GB 94) is a tetracyclic compound with antidepressant effects. it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors. It may cause drowsiness and hematological problems.
    • $32
    In Stock
    Size
    QTY
  • Gramine
    T651987-52-5
    Gramine (Donaxine), a natural indole alkaloid, present in several plant species, acts as an active adiponectin receptor (AdipoR) agonist, with IC50s of 3.2 and 4.2 μM for AdipoR2 and AdipoR1, respectively. Gramine is also a human and mouse β2-Adrenergic receptor (β2-AR) agonist. Gramine has anti-tumor, anti-viral and anti-inflammatory properties.
    • $38
    In Stock
    Size
    QTY
  • Adrenalone hydrochloride
    T094862-13-5
    Adrenalone hydrochloride (Adrenalone HCl) is a dopamine β-oxidase inhibitor with a similar structure to the norepinephrine transporter (NET) ligand, with an IC50 of 36.9 μM. It is an adrenergic agonist that acts as a local vasoconstrictor and hemostatic agent.
    • $50
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Sale
  • Buflomedil hydrochloride
    T031735543-24-9
    Buflomedil hydrochloride (Fonzylane), a vasodilator, is used in therapy of claudication or the symptoms of the peripheral arterial disease.
    • $58
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Sale
  • Anisodamine Hydrobromide
    T830455449-49-5
    Anisodamine Hydrobromide (6-Hydroxyhyoscyamine) is an anticholinergic and α1-adrenergic receptor antagonist used in the treatment of acute circulatory shock.
    • $66
    In Stock
    Size
    QTY
  • Perphenazine
    T109058-39-9
    Perphenazine (Trilafon) is a phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties.
    • $29
    In Stock
    Size
    QTY
    TargetMol | Citations Cited
  • Butofilolol
    T6077358930-32-8In house
    Butofilolol is a novel beta-blocker with antihypertensive activity and can be used to study hypertension.
    • $293 TargetMol
    In Stock
    Size
    QTY
  • Salbutamol
    T113918559-94-9
    Salbutamol (Albuterol) stimulates beta2-adrenergic receptors in the lungs, thereby activating the enzyme adenylate cyclase that catalyzes the conversion of ATP to cyclic-3', 5'-adenosine monophosphate (cAMP). Salbutamol Sulfate is the sulfate salt of the short-acting sympathomimetic agent albuterol, a 1:1 racemic mixture of (R)-albuterol and (S)-albuterol with bronchodilator activity. Increased cAMP concentrations relax the bronchial smooth muscle, relieve bronchospasms, and reduce inflammatory cell mediator release, especially from mast cells. To a lesser extent, Salbutamol stimulates beta1-adrenergic receptors, thereby increasing the force and rate of myocardial contraction.
    • $30
    In Stock
    Size
    QTY
  • Medetomidine hydrochloride
    T657986347-15-1
    Medetomidine hydrochloride (MPV785) is a selective α2-adrenoceptor agonist, with Ki of 1.08 nM, exhibts 1620-fold selectivity over α1-adrenoceptor.
    • $48
    In Stock
    Size
    QTY
  • RS 17053 hydrochloride
    T16798169505-93-5In house
    RS 17053 hydrochloride is a potent and selective antagonist of α1A adrenoceptor. RS 17053 hydrochloride exhibits a pKi value of 9.1 in native cell membrane and a pA2 value of 9.8 in functional assays.
    • $34
    In Stock
    Size
    QTY
  • Tamsulosin hydrochloride
    T0210106463-17-6In house
    Tamsulosin hydrochloride (Flomax hydrochloride) is the hydrochloride salt of tamsulosin, a sulfonamide derivative with α1 adrenergic antagonist activity.
    • $30 TargetMol
    In Stock
    Size
    QTY
  • Trazodone hydrochloride
    T161925332-39-2
    Trazodone hydrochloride (Trazodone HCl) is a serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and other subsets of depressive disorders. It is generally more useful in depressive disorders associated with insomnia and anxiety.
    • $39
    In Stock
    Size
    QTY
  • MG 1
    T12030148274-76-4In house
    MG 1 is a potent alpha-1 adrenergic receptor antagonist.
    • $700
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Sale
  • Taxifolin
    T1738480-18-2
    Taxifolin (Dihydroquercetin) is a flavonoid in many plants such as Taxus chinensis, Siberian larch, Cedrus deodara and so on.
    • $46
    In Stock
    Size
    QTY
    TargetMol | Citations Cited
  • OPC-28326
    T13804167626-17-7In house
    OPC-28326 is a specific an α2-adrenergic receptor antagonist and acts as a peripheral vasodilator. OPC-28326 inhibits α2A-, α2B- and α2C-adrenoceptors with Ki of 2040, 285, and 55 nM, respectively.
    • $329
    In Stock
    Size
    QTY
  • Faxeladol
    T31750433265-65-7In house
    Faxeladol, a potent adrenergic absorption inhibitor and serotonin reuptake inhibitor, is a small-molecule Opioid receptor agonist that can be used to study neurological disorders.
    • $628
    In Stock
    Size
    QTY
  • Taprizosin
    T28922210538-44-6In house
    Taprizosin(UK-338003) is a selective and orally active α1-adrenoceptor antagonist for vasodilatation in the treatment of benign prostatic hyperplasia.
    • $373
    In Stock
    Size
    QTY
  • Tolazoline
    T2144759-98-3
    Tolazoline (Benzalolin), a non-selective competitive α-adrenergic receptor antagonist, is used as a vasodilator to treat spasms of peripheral blood vessels. It has also been used successfully as an antidote to reverse the severe peripheral vasoconstriction as a result of overdose with certain 5-HT2A agonist drugs.
    • $50
    In Stock
    Size
    QTY
  • (4E)-SUN9221
    T12596222318-55-0
    (4E)-SUN9221 is a potent dual α1-adrenergic receptor and 5-HT2 receptor antagonist that shows antihypertensive and antiplatelet aggregation activity in hypertensive rats.
    • $700
    In Stock
    Size
    QTY
  • T-0509
    T2889596843-99-1In house
    T-0509 is a selective beta 1 receptor agonist that increases inotropy in canine ventricular muscle and selectively down-regulates rat cardiac beta 1-adrenoceptors.
    • $350
    In Stock
    Size
    QTY
  • (S)-(-)-Atenolol
    T3583393379-54-5In house
    (S)-(-)-Atenolol has beta-adrenergic blocking effects.
    • $67 TargetMol
    In Stock
    Size
    QTY
  • (S)-(+)-Niguldipine hydrochloride
    T23301113145-69-0In house
    (S)-(+)-Niguldipine hydrochloride is a selective α1A-AR antagonist used in the study of depression and epilepsy.
    • $75 TargetMol
    In Stock
    Size
    QTY
  • ACTH 1-14 acetate(25696-21-3 free base)
    TP1238L
    ACTH 1-14 acetate(25696-21-3 free base) (Adrenocorticotropic Hormone Fragment 1-14 acetate) is a fragment of adrenocorticotrophin, which regulates cortisol and androgen production.Adrenocorticotropic hormone (ACTH), also known as corticotropin, is produced and secreted by the anterior pituitary gland. ACTH is an important component of the hypothalamic-pituitary-adrenal axis as a response to biological stress.
    • $78
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Sale
  • LUN42518 HCl 47142-51-8(free base)
    T8738
    LUN42518 HCl is an analogue of phentolamine. Phentolamine is a nonselective alpha-adrenergic antagonist.
    • $133
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Sale
  • RS 15385-198
    T68051L121961-55-5In house
    RS 15385-198 is a less active isomer of Delequamine. Delequamine is a selective alpha2-adrenergic receptor antagonist.
    • $195
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Sale
  • L-745870 trihydrochloride
    T22904866021-03-6
    L-745870 trihydrochloride is a highly potent and selective D4 dopamine receptor antagonist.
    • $68
    In Stock
    Size
    QTY
  • Nardeterol HCl
    T68114L In house
    Nardeterol HCl is a β-adrenergic receptor partial agonist used in the study of the central nervous system.CAS 번호13460-73-83-4
    • $249 TargetMol
    In Stock
    Size
    QTY
  • Esprolol
    T27286L396654-09-4In house
    Esprolol (ACC-9369 free base) is a novel β-adrenergic receptor antagonist for the study of exertional angina.
    • $129 TargetMol
    In Stock
    Size
    QTY
  • Dabelotine
    T31175118976-38-8In house
    Dabelotine (UNII-6RY56RB98P) is an adrenergic agonist used in the study of dementia.
    • $146
    In Stock
    Size
    QTY
  • Neldazosin
    T61535109713-79-3In house
    Neldazosin is used as a potent α1-adrenoceptor antagonist.
    • $210
    In Stock
    Size
    QTY
  • Fipamezole
    T24064150586-58-6In house
    Fipamezole is a potent alpha2 adrenergic receptor antagonist that may be useful for studying autonomic dysfunction in Parkinson's disease.
    • $628
    In Stock
    Size
    QTY
  • Aplindore Fumarate
    T30098189681-71-8In house
    Aplindore Fumarate (DAB-452) is a small molecule dopamine D2 receptor partial agonist.Aplindore Fumarate exhibits high affinity for dopamine D2 and D3 receptors, and low affinity for dopamine D4, 5-hydroxytryptophan (5-HT2), and α1-adrenergic receptors.Aplindore Fumarate is used in the study of Parkinson's disease and schizophrenia. Fumarate can be used to study Parkinson's and schizophrenia.
    • $293
    In Stock
    Size
    QTY
  • Rezatomidine
    T34308847829-38-3
    Rezatomidine (AGN203818) is a selective antagonist of α2-adrenergic receptor and can be used in studies about chronic pain, including neuropathic pain.
    • $195
    In Stock
    Size
    QTY
  • TD-5471 hydrochloride
    T13106530084-35-6
    TD-5471 hydrochloride is a selective and potent long-acting human β2-adrenergic receptor agonist for the treatment of chronic obstructive pulmonary disease (COPD).
    • $700
    Backorder
    Size
    QTY
  • Deriglidole
    T10998122830-14-2In house
    Deriglidole (SL 86-0715) is a peripheral adrenergic receptor antagonist that is a selective inhibitor of alpha2 receptors. Deriglidole inhibits colistin and Idazoxan but does not show activity against prazosin and rat cortical and human platelet α2-adrenergic receptors.
    • $460
    In Stock
    Size
    QTY
  • N-methyltyramine
    TN7042370-98-9
    N-methyltyramine is an alkaloid isolated from the leguminous plant Acacia grandiflora.It is an α2-adrenoceptor antagonist that regulates adrenergic receptors through enzymatic adrenergic synthesis.It is used in the study of intestinal disorders.N-methyltyramine has been used in the study of intestinal disorders.N-methyltyramine has been used in the study of intestinal disorders.
    • $52
    Backorder
    Size
    QTY
  • Imiloxan
    T2759981167-16-0In house
    Imiloxan (RS-21361) is an α2 adrenergic receptor antagonist used in the treatment of major depressive disorder.
    • $413 TargetMol
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Sale
  • Tolnapersine TFA
    T68023L
    Tolnapersine TFA is a mixed dopamine agonist and alpha adrenergic receptor antagonist.
    • $195
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Sale