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CP21R7

🥰Excellent
Catalog No. T3684Cas No. 125314-13-8
Alias CP21

CP21R7 (CP21) is an effective and specific GSK3β inhibitor. It is used as an activator of stem cells prior to the induction of differentiation of stem cells to smooth muscle and endothelial cells. CP21R7 can be combined with BMP4 to commit human pluripotent stem cells to a mesodermal fate.

CP21R7
Other Forms of CP21R7:
CP21T7187030652-12-1
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CP21R7

🥰Excellent
Purity: 99.16%
Catalog No. T3684Alias CP21Cas No. 125314-13-8
CP21R7 (CP21) is an effective and specific GSK3β inhibitor. It is used as an activator of stem cells prior to the induction of differentiation of stem cells to smooth muscle and endothelial cells. CP21R7 can be combined with BMP4 to commit human pluripotent stem cells to a mesodermal fate.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$35In StockIn Stock
5 mg$84In StockIn Stock
10 mg$137In StockIn Stock
25 mg$277In StockIn Stock
50 mg$416In StockIn Stock
100 mg$625-In Stock
200 mg$883-In Stock
1 mL x 10 mM (in DMSO)$74In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.16%
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
CP21R7 (CP21) is an effective and specific GSK3β inhibitor. It is used as an activator of stem cells prior to the induction of differentiation of stem cells to smooth muscle and endothelial cells. CP21R7 can be combined with BMP4 to commit human pluripotent stem cells to a mesodermal fate.
Targets&IC50
GSK-3β:1.8 nM, PKCα:1900 nM.
SynonymsCP21
Chemical Properties
Molecular Weight317.34
FormulaC19H15N3O2
Cas No.125314-13-8
SmilesCn1cc(C2=C(C(=O)NC2=O)c2cccc(N)c2)c2ccccc12
Relative Density.1.37 g/cm3 (Predicted)
ColorRed
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
Ethanol: 1 mg/mL (3.15 mM), Sonication is recommended.
DMSO: 59 mg/mL (185.92 mM), Sonication is recommended.
H2O: < 1 mg/mL (insoluble or slightly soluble)
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (6.3 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
Ethanol/DMSO
1mg5mg10mg50mg
1 mM3.1512 mL15.7560 mL31.5119 mL157.5597 mL
DMSO
1mg5mg10mg50mg
5 mM0.6302 mL3.1512 mL6.3024 mL31.5119 mL
10 mM0.3151 mL1.5756 mL3.1512 mL15.7560 mL
20 mM0.1576 mL0.7878 mL1.5756 mL7.8780 mL
50 mM0.0630 mL0.3151 mL0.6302 mL3.1512 mL
100 mM0.0315 mL0.1576 mL0.3151 mL1.5756 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

PKCαGSK-3βGSK-3GSK3CP-21R7CP21R7CP-21CP 21
Related Tags: buy CP21R7 | purchase CP21R7 | CP21R7 cost | order CP21R7 | CP21R7 chemical structure | CP21R7 formula | CP21R7 molecular weight
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