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Anti-Phospho-Cardiac phospholamban/PLN (Ser16, T17) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Cardiac phospholamban/PLN (Ser16, T17). Anti-Phospho-Cardiac phospholamban/PLN (Ser16, T17) Polyclonal Antibody can be used in ICC/IF,ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $217 | 7-10 days | |
100 μL | $317 | 7-10 days |
Description | Anti-Phospho-Cardiac phospholamban/PLN (Ser16, T17) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Cardiac phospholamban/PLN (Ser16, T17). Anti-Phospho-Cardiac phospholamban/PLN (Ser16, T17) Polyclonal Antibody can be used in ICC/IF,ELISA. |
Ig Type | IgG |
Reactivity | Human,Mouse,Rat |
Application | |
Recommended Dose | ICC/IF: 1:200-1000; ELISA: 1:10000 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Construction | Polyclonal Antibody |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Appearance | Liquid |
Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Research Background | phospholamban(PLN) Homo sapiens The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in this gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure, and also familial hypertrophic cardiomyopathy. [provided by RefSeq, Apr 2016], |
Conjucates | Unconjugated |
Others Formats | Phospho |
Immunogen | A synthesized phosphopeptide: human PLB around the phosphorylation site of Ser16 and Thr17. AA range:1-50 |
Antigen Species | human |
Uniprot ID |
Molecular Weight | Theoretical: 6 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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