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Anti-Carboxypeptidase B2 Antibody (9H703)
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Catalog No. TMAY-03501
Alias carboxypeptidase B2 (plasma)
Anti-Carboxypeptidase B2 Antibody (9H703) is a Rabbit antibody targeting Carboxypeptidase B2. Anti-Carboxypeptidase B2 Antibody (9H703) can be used in ELISA.
Anti-Carboxypeptidase B2 Antibody (9H703)
Anti-Carboxypeptidase B2 Antibody (9H703)
😃Good
Catalog No. TMAY-03501Alias carboxypeptidase B2 (plasma)
Anti-Carboxypeptidase B2 Antibody (9H703) is a Rabbit antibody targeting Carboxypeptidase B2. Anti-Carboxypeptidase B2 Antibody (9H703) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Carboxypeptidase B2 Antibody (9H703) is a Rabbit antibody targeting Carboxypeptidase B2. Anti-Carboxypeptidase B2 Antibody (9H703) can be used in ELISA. |
| Alias | carboxypeptidase B2 (plasma) |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 9H703 |
| Reactivity | Mouse |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Carboxypeptidase B2 / CPB2 (TMPY-02505; Q9JHH6; Met1-Thr422). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Carboxypeptidase B2, also known as Carboxypeptidase U, Thrombin-activable fibrinolysis inhibitor, Plasma carboxypeptidase B, CPB2, is a secreted protein which belongs to the peptidase M14 family. Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). CPB2 is activated by thrombin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. CPB2 is synthesized by the liver and circulates in the plasma as a plasminogen-bound zymogen. When it is activated by proteolysis at residue Arg92 by the thrombin / thrombomodulin complex. CPB2 cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. CPB2 exhibits carboxypeptidase activity and activated CPB2 reduces fibrinolysis by removing the fibrin C-terminal residues that are important for the binding and activation of plasminogen. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Mouse Carboxypeptidase B2 / CPB2 protein (TMPY-02505) |
| Antigen Species | Mouse |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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