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Anti-SCGN Antibody (2S109) (Synonyms: setagin, SEGN, secretagogin, EF-hand calcium binding protein, SECRET, ...)
Catalog No. TMAY-02341 Copy Product Info
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Anti-SCGN Antibody (2S109) is a Rabbit antibody targeting SCGN. Anti-SCGN Antibody (2S109) can be used in IHC-P.
Anti-SCGN Antibody (2S109)
Copy Product Info🥰Excellent
Catalog No. TMAY-02341
Synonyms setagin, SEGN, secretagogin, EF-hand calcium binding protein, SECRET, DJ501N12.8, CALBL
Anti-SCGN Antibody (2S109) is a Rabbit antibody targeting SCGN. Anti-SCGN Antibody (2S109) can be used in IHC-P.
Anti-SCGN Antibody
(2S109)
(2S109)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 100 μL | $269 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-SCGN Antibody (2S109) is a Rabbit antibody targeting SCGN. Anti-SCGN Antibody (2S109) can be used in IHC-P. |
| Synonyms | setagin, SEGN, secretagogin, EF-hand calcium binding protein, SECRET, DJ501N12.8, CALBL |
| Ig Type | Rabbit IgG |
| Clone | 2S109 |
| Reactivity | Human |
| Specificity | Human SCGN |
| Verified Activity | Immunochemical staining of human SCGN in human pancreas (from 2 donors) with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). |
| Application | |
| Recommended Dose | IHC-P: 1:100-1:500 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human SCGN / Secretagogin (rh SCGN / Secretagogin; TMPY-01875; NP_008929.2; Asp2-Pro276). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Secretagogin, also known as SCGN, is a secreted protein that is detectable in human serum after ischemic neuronal damage. It is a recently described calcium-binding protein. Secretagogin / SCGN is expressed at high levels in the pancreatic islets of Langerhans and to a much lesser extent in the gastrointestinal tract (stomach, small intestine and colon), the adrenal medulla and cortex and the thyroid C-cells. In the brain, the expression of Secretagogin / SCGN is restricted to distinct subtypes of neurons with highest expression in the molecular layer of the cerebellum (stellate and basket cells), in the anterior part of the pituitary gland, in the thalamus, in the hypothalamus and in a subgroup of neocortical neurons. Secretagogin / SCGN is widely expressed in prostatic adenocarcinoma as opposed to adenocarcinomas in other organs. The function of Secretagogin / SCGN is unknown, but it has been suggested in beta-cells to influence calcium-influx and has been observed downregulated in diabetes-prone BB rat islets exposed to cytokines. Secretagogin / SCGN is involved in the calcium metabolism of tumour cells and endothelial cells in a subset of neoplasms of the brain and its coverings. Secretagogin / SCGN is also a novel marker for neuroendocrine differentiation. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human SCGN / Secretagogin protein (TMPY-01875) |
| Antigen Species | Human |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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