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HAMP Protein, Human, Recombinant (GST)

Catalog No. TMPJ-01062
Synonyms: Liver-expressed antimicrobial peptide 1, HEPC, LEAP1, Putative liver tumor regressor

Hepcidin(HAMP)is a secreted protein that belongs to the hepcidin family.It is expressed in liver, heart and brain. It is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta sheet structures.

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HAMP Protein, Human, Recombinant (GST)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 184.00
50 μg 5 days $ 545.00
500 μg 5 days $ 2,070.00
1 mg 5 days $ 2,970.00
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Biological Description
Technical Params
Product Properties
Description Hepcidin(HAMP)is a secreted protein that belongs to the hepcidin family.It is expressed in liver, heart and brain. It is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta sheet structures.
Species Human
Expression System E. coli
Tag N-GST
Accession Number P81172
Synonyms Liver-expressed antimicrobial peptide 1, HEPC, LEAP1, Putative liver tumor regressor
Amino Acid Asp60-Thr84
Construction Recombinant Human Hepcidin is produced by our E.coli expression system and the target gene encoding Asp60-Thr84 is expressed with a GST tag at the N-terminus.
Protein Purity Greater than 85% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 28-30 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Supplied as a 0.2 μm filtered solution of PBS, 50% Glycerol, pH 7.4.
Stability & Storage

Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Shipping

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

Research Background Hepcidin(HAMP)is a secreted protein that belongs to the hepcidin family.It is expressed in liver, heart and brain. It is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta sheet structures.

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Keywords

HAMP Protein, Human, Recombinant (GST) LEAP-1 LEAP 1 Liver-expressed antimicrobial peptide 1 HEPC LEAP1 Putative liver tumor regressor recombinant recombinant-proteins proteins protein

 

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