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Anti-Serpin A3 Antibody (4M969)
😃Good
Catalog No. TMAY-00591
Alias SERPINA3, serpin peptidase inhibitor, clade A (α-1 antiproteinase, antitrypsin), member 3, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3, MGC88254, GIG25, GIG24, ACT, AACT
Anti-Serpin A3 Antibody (4M969) is a Mouse antibody targeting Serpin A3. Anti-Serpin A3 Antibody (4M969) can be used in ELISA.
Anti-Serpin A3 Antibody (4M969)
Anti-Serpin A3 Antibody (4M969)
😃Good
Catalog No. TMAY-00591Alias SERPINA3, serpin peptidase inhibitor, clade A (α-1 antiproteinase, antitrypsin), member 3, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3, MGC88254, GIG25, GIG24, ACT, AACT
Anti-Serpin A3 Antibody (4M969) is a Mouse antibody targeting Serpin A3. Anti-Serpin A3 Antibody (4M969) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $292 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: ELISA Reactivity: Human |
| Alias | SERPINA3, serpin peptidase inhibitor, clade A (α-1 antiproteinase, antitrypsin), member 3, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3, MGC88254, GIG25, GIG24, ACT, AACT |
| Ig Type | Mouse IgG1 |
| Clone | 4M969 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human SerpinA3 (rh SerpinA3; TMPY-01303; NP_001076.2; Met 1-Ala 423). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | SerpinA3, also known as Alpha 1-antichymotrypsin (AACT), is a plasma alpha globulin glycoprotein, and is a member of serpin superfamily of the serine protease inhibitors consisting of at least 35 members. SerpinA3 has been demonstrated to inhibit the activity of certain serine proteases, such as cathepsin G found in neutrophils, and chymases present in mast cells, by inducing a major conformational rearrangement, and thus protects some tissues from damage caused by proteolytic enzymes. This enzyme is produced primarily in the liver, and is identified as an acute-phase inflammatory protein. SerpinA3 deficiency has been associated with liver disease, and mutations of this gene have been observed in patients with Parkinson disease and chronic obstructive pulmonary disease. Besides, ACT gene polymorphism has been implicated with Alzheimer’s disease (AD), cerebral amyloid angiopathy (CAA), as well as stroke, since SerpinA3 is a major constituent of the plaques in AD and an inhibitor of amyloid beta peptide degradation. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human SerpinA3 protein (TMPY-01303) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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