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Anti-CD10 Antibody (8O420)
😃Good
Catalog No. TMAY-01180
Alias membrane metallo-endopeptidase
Anti-CD10 Antibody (8O420) is a Mouse antibody targeting CD10. Anti-CD10 Antibody (8O420) can be used in IHC-P.
Anti-CD10 Antibody (8O420)
Anti-CD10 Antibody (8O420)
😃Good
Catalog No. TMAY-01180Alias membrane metallo-endopeptidase
Anti-CD10 Antibody (8O420) is a Mouse antibody targeting CD10. Anti-CD10 Antibody (8O420) can be used in IHC-P.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $199 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CD10 Antibody (8O420) is a Mouse antibody targeting CD10. Anti-CD10 Antibody (8O420) can be used in IHC-P. |
| Alias | membrane metallo-endopeptidase |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 8O420 |
| Reactivity | Human |
| Verified Activity | 1. Immunochemical staining of human MME in human kidney with mouse monoclonal antibody at 1:60 dilution, formalin-fixed paraffin embedded sections. 2. Immunochemical staining of human MME in human lymphoma with mouse monoclonal antibody at 1:60 dilution, formalin-fixed paraffin embedded sections. |
| Application | IHC-P |
| Recommended Dose | IHC-P: 1:30-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD10/Neprilysin/MME (rh CD10/Neprilysin/MME; TMPY-02315; NP_000893.2; Tyr52-Trp750). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alters the behavior of the cell. Some CD proteins do not take part in the cell signal process but have other functions such as cell adhesion. The cluster of differentiation 10 (CD10), also known as Neprilysin and neutral endopeptidase, is a member of the CD system. CD10 is a zinc-dependent metalloprotease enzyme that had the function to degrade some small secreted peptides such as the amyloid beta-peptide. It exists as a membrane-bound protein and has a high concentration in kidney and lung tissues. Mutations in the CD10 gene can induce the familial forms of Alzheimer's disease, providing strong evidence for the protein's association with the Alzheimer's disease process. CD10 is also associated with other biochemical processes. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human CD10/Neprilysin/MME Protein (TMPY-02315) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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