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PROTAC
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PROTAC Linker
PROTAC linker plays a vital role in efficient ubiquitination of the target protein and its ultimate degradation. To date, several kinds of linkers have been reported and applied in PROTAC ternary complexes formation, such as PEG linker, Alkyl linker, alkyne linkers, and click chemistry linker, etc.
- Ac4ManNAzT14093361154-30-5In houseAc4ManNAz is an azido-containing metabolic glycoprotein labeling reagent. It can be used to selectively modify proteins, and it can be used in cell labeling, tracking and proteomic analysis;
- $32
SizeQTY
- Boc-NH-PEG8-CH2CH2COOHT176831334169-93-5Boc-NH-PEG8-CH2CH2COOH is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
- $29
SizeQTY
- Boc-NH-PEG8-CH2CH2NH2T176841052207-59-6Boc-NH-PEG8-CH2CH2NH2 is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
- $29
SizeQTY - Boc-NH-O-C1-NHS esterT1765580366-85-4Boc-NH-O-C1-NHS ester is an alkyl ether-based PROTAC linker that can be used in PROTAC synthesis.
- $29
SizeQTY - Boc-C16-COOHT9783843666-40-0Boc-C16-COOH is a alkyl-chain-based PROTAC linker. Boc-C16-COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
- $40
SizeQTY - Fmoc-NH-PEG10-acidT179642101563-45-3Fmoc-NH-PEG10-acid is a PEG-based PROTAC linker. Fmoc-NH-PEG10-acid can be used in the synthesis of PROTACs.
- $29
SizeQTY - Azido-PEG10-alcoholT14413877239-09-3Azido-PEG10-alcohol is a PEG-based PROTAC linker that can be used in PROTAC synthesis[1].
- $29
SizeQTY - Hydroxy-PEG5-BocT15534850090-09-4Hydroxy-PEG6-Boc is a PEG-based PROTAC linker that can be used in PROTAC synthesis[1].
- $29
SizeQTY - Azido-PEG12-acidT174842152679-71-3Azido-PEG12-acid is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
- $41
SizeQTY - Azido-PEG1-azideT1747624345-74-2Azido-PEG1-azide is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
- $29
SizeQTY - Boc-NH-PEG3-NHS esterT176772250216-93-2Boc-NH-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
- $64
SizeQTY - m-PEG16-alcoholT18151133604-58-7m-PEG16-alcohol is a PEG-based PROTAC linker. m-PEG16-alcohol can be used in the synthesis of PROTACs.
- $29
SizeQTY - 1,3-Dibromo-5,5-dimethylhydantoinT1732177-48-51,3-Dibromo-5,5-dimethylhydantoin is an alkyl chain-based PROTAC linker that can be used in PROTAC synthesis.
- $29
SizeQTY - m-PEG7-BrT18215104518-25-4m-PEG7-Br is a PEG-based PROTAC linker. m-PEG7-Br can be used in the synthesis of PROTACs.
- $29
SizeQTY - Amino-PEG4-BocT14238581065-95-4Amino-PEG4-Boc is a PEG-based PROTAC linker that can be used in PROTAC synthesis[1].
- $29
SizeQTY - m-PEG9-SHT18229651042-84-1m-PEG9-SH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
- $47
SizeQTY - Mal-PEG5-BocT182952250216-91-0Mal-PEG5-Boc (Mal-PEG5-COOtBu) is a PEG-based PROTAC linker. Mal-PEG5-Boc can be used in the synthesis of PROTACs.
- $50
SizeQTY - Mal-amido-PEG7-acidT159602112731-42-5Mal-amido-PEG7-acid (Mal-NH-PEG7-COOH) is a PEG-based PROTAC linker that can be used to synthesize PROTACs.
- $195
SizeQTY - Hydroxy-PEG10-acidT180312375611-66-6Hydroxy-PEG10-acid (HO-PEG10-CH2CH2COOH) is a PEG-based PROTAC linker that can be used to synthesize PROTACs[1].
- $50
SizeQTY - Propargyl-PEG12-bromideT185662410937-34-5Propargyl-PEG12-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
- $95
SizeQTY - Propargyl-PEG5-MsT185881036204-62-2Propargyl-PEG5-Ms (Propargyl-PEG6-Ms) is a PEG-based PROTAC linker. Propargyl-PEG5-Ms can be used in the synthesis of PROTACs.
- $92
SizeQTY - Propargyl-PEG11-methaneT185682250411-18-6Propargyl-PEG11-methane is a PEG-based PROTAC linker that can be used to synthesize PROTACs[1].
- $56
SizeQTY - DSPE-PEG-OH (MW 2000)T17854DSPE-PEG-OH (MW 2000) is a PEG-based PROTAC linker for PROTAC synthesis.
- $133
SizeQTY - Amino-PEG7-acidT174402376111-92-9Amino-PEG7-acid is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
- $55
SizeQTY - m-PEG11-BrT181251258596-39-2m-PEG11-Br is a PEG-based PROTAC linker. m-PEG11-Br can be used in the synthesis of PROTACs.
- $50
SizeQTY - Cbz-NH-PEG12-C2-acidT177191334177-88-6Cbz-NH-PEG12-C2-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
- $53
SizeQTY - Aminooxy-PEG4-alcoholT14271106492-60-8Aminooxy-PEG4-alcohol is both a non-cleavable 4-unit PEG ADC linker and a PEG-based PROTAC linker.
- $50
SizeQTY - Bis-Tos-PEG7T1763669502-27-8Bis-Tos-PEG7 is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
- $30
SizeQTY - m-PEG16-BrT181531238189-11-1m-PEG16-Br is a PEG-based PROTAC linker. m-PEG16-Br can be used in the synthesis of PROTACs.
- $53
SizeQTY - Propargyl-PEG17-methaneT185742169967-47-7Propargyl-PEG17-methane (MPEG16-Propyne) is a PEG-based PROTAC linker. Propargyl-PEG17-methane can be used in the synthesis of PROTACs.
- $40
SizeQTY - 2,3,4,6-Tetra-o-acetyl-alpha-galactosylpyranosyl bromideT17326529493-92-32,3,4,6-Tetra-o-acetyl-alpha-galactosylpyranosyl bromide (2-3-4-6-tetra-o-acetyl-alpha-galactosylpyranosyl-bromide) is an alkyl chain-based PROTAC linker that can be used in PROTAC synthesis.
- $37
SizeQTY - Azido-PEG11-alcoholT174822252392-53-1Azido-PEG11-alcohol is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
- $98
SizeQTY - Cbz-NH-PEG5-CH2COOHT177241449390-66-2Cbz-NH-PEG5-CH2COOH is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
- $77
SizeQTY - Azido-PEG12-NHS esterT174862363756-50-5Azido-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
- $37
SizeQTY - Azide-PEG12-TosT174651821464-56-5Azide-PEG12-Tos is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
- $38
SizeQTY - 2-Phthalimidehydroxy-acetic acidT17330134724-87-12-Phthalimidehydroxy-acetic acid is an alkyl chain-based PROTAC linker that can be used in PROTAC synthesis.
- $59
SizeQTY - NH2-PEG6-C1-BocT18494297162-50-6NH2-PEG6-C1-Boc (H2N-PEG6-CH2COOtBu) is a PEG-based PROTAC linker. NH2-PEG6-C1-Boc can be used in the synthesis of PROTACs.
- $50
SizeQTY - Biotin-PEG6-BocT175911352814-07-3Biotin-PEG6-Boc (Biotin-PEG6-t-butyl ester) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
- $51
SizeQTY - Bromo-PEG1-C2-azideT176981144106-65-9Bromo-PEG1-C2-azide is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
- $33
SizeQTY - Acid-C1-PEG5-BocT173522304558-22-1Acid-C1-PEG5-Boc is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
- $39
SizeQTY - Azido-PEG9-azideT175221171122-72-7Azido-PEG9-azide is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
- $98
SizeQTY - Amino-PEG14-alcoholT1741334214-89-6Amino-PEG14-alcohol (H2N-PEG14-OH) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
- $47
SizeQTY - Boc-NH-PEG7-TosT176821292268-14-4Boc-NH-PEG7-Tos (t-Boc-N-Amido-PEG7-Tos) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
- $31
SizeQTY - Azido-PEG4-azideT39268182760-73-2Azido-PEG4-azide is a PEG-based PROTAC linker that can be used to synthesize PROTACs.
- $50
SizeQTY - m-PEG7-4-nitrophenyl carbonateT15919678150-56-6m-PEG7-4-nitrophenyl carbonate is a PEG-based PROTAC linker that can be used in PROTAC synthesis[1].
- $65
SizeQTY - 5-Ethynyl-2'-deoxyuridineT1734161135-33-95-Ethynyl-2'-deoxyuridine (EdU) is a nucleoside analog of thymidine that is used to monitor de novo DNA synthesis through click chemistry.It is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
- $33
SizeQTY
Cited - TGN-020T510251987-99-6TGN-020 is an inhibitor of Aquaporin 4 (AQP4, IC50: 3.1 μM), the most abundant water channel in the brain.
- $47
SizeQTY Cited - N-Boc-4-pentyne-1-amineT18391151978-50-6N-Boc-4-pentyne-1-amine is an alkyl chain-based PROTAC linker compound utilized in the synthesis of PROTAC MG-277[1].
- $50
SizeQTY - Pomalidomide-PEG3-C2-NH2T178832093416-31-8Pomalidomide-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 5) is a synthesized E3 ligase ligand-linker conjugate incorporating the Pomalidomide based cereblon ligand and 3-unit PEG linker.
- $195
SizeQTY - Fmoc-Lys-OH hydrochlorideT41312139262-23-0Fmoc-Lys-OH hydrochloride is a alkyl-chain-based PROTAC linker. Fmoc-Lys-OH hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
- $29
SizeQTY
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