Home Tools
Log in
Cart

PROTAC Linker

PROTAC linker plays a vital role in efficient ubiquitination of the target protein and its ultimate degradation. To date, several kinds of linkers have been reported and applied in PROTAC ternary complexes formation, such as PEG linker, Alkyl linker, alkyne linkers, and click chemistry linker, etc.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T17883 Pomalidomide-PEG3-C2-NH2 2093416-31-8 98%
Pomalidomide-PEG3-C2-NH2
Pomalidomide-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 5) is a synthesized E3 ligase ligand-linker conjugate incorporating the Pomalidomide based cereblon l...
T40858 NH2-PEG2-C6-Cl 744203-60-9 98%
NH2-PEG2-C6-Cl
NH2-PEG2-C6-Cl is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein d...
T18487 NH2-C6-NH-Boc 51857-17-1 99.97%
NH2-C6-NH-Boc
NH2-C6-NH-Boc is a PROTAC linker. NH2-C6-NH-Boc can be used in the synthesis the Mcl-1 inhibitor based on PROTAC.
T18546 (+)-Biotin-ONP 33755-53-2 99.91%
(+)-Biotin-ONP
(+)-Biotin-ONP ((+)-Biotin 4-nitrophenyl ester) is an alkyl chain-based PROTAC linker. (+)-Biotin-ONP can be used in the synthesis of PROTACs.
T18485 NH2-C4-NH-Boc 68076-36-8 99.90%
NH2-C4-NH-Boc
NH2-C4-NH-Boc (compound 15) is a PROTAC linker belonging to the Alkyl/ether class. NH2-C4-NH-Boc can be used to synthesize a series of PROTAC molecules.
T17352 Acid-C1-PEG5-Boc 2304558-22-1 99.89%
Acid-C1-PEG5-Boc
Acid-C1-PEG5-Boc is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
T17637 BM-PEG3 86099-06-1 99.87%
BM-PEG3
BM-PEG3 (1,11-Bis-maleimidotetraethyleneglycol) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
T14746 Boc-NH-PEG4-CH2COOH 876345-13-0 99.84%
Boc-NH-PEG4-CH2COOH
Boc-NH-PEG4-CH2COOH is a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC)[1].
T16486 Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD 1037589-69-7 99.83%
Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD
Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD (PF-05231023) is a long-acting fibroblast growth factor 21 (FGF21) analog and is an FGF21-receptor agonist. It is also suita...
T17348 Ac4GalNAz 653600-56-7 99.81%
Ac4GalNAz
Ac4GalNAz is an alkyl chain-based PROTAC linker that can be used in PROTAC synthesis.
T4546 Dinoprost tromethamine salt 38562-01-5 99.73%
Dinoprost tromethamine salt
Dinoprost tromethamine salt (PGF2α THAM) is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient.
T17408 Amino-PEG12-Boc 1383814-00-3 99.68%
Amino-PEG12-Boc
Amino-PEG12-Boc is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
T17716 Cbz-NH-PEG1-CH2CH2COOH 1205751-19-4 99.67%
Cbz-NH-PEG1-CH2CH2COOH
Cbz-NH-PEG1-CH2CH2COOH is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
T17549 Biotin-EDA 111790-37-5 99.66%
Biotin-EDA
Biotin-EDA is an alkyl chain-based PROTAC linker that can be used in PROTAC synthesis.
T17638 Boc-11-aminoundecanoic acid 10436-25-6 99.64%
Boc-11-aminoundecanoic acid
Boc-11-aminoundecanoic acid is an Alkyl/ether-based PROTAC linker that can be used in the synthesis of MS432.
T14271 Aminooxy-PEG4-alcohol 106492-60-8 99.64%
Aminooxy-PEG4-alcohol
Aminooxy-PEG4-alcohol is both a non-cleavable 4-unit PEG ADC linker and a PEG-based PROTAC linker.
T15304 Fmoc-8-amino-3,6-dioxaoctanoic acid 166108-71-0 99.61%
Fmoc-8-amino-3,6-dioxaoctanoic acid
Fmoc-8-amino-3,6-dioxaoctanoic acid (Fmoc-NH-PEG2-CH2COOH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It is also a PEG-b...
T40728 1-Bromo-6-chlorohexane 6294-17-3 99.58%
1-Bromo-6-chlorohexane
1-Bromo-6-chlorohexane (Hexane, 1-bromo-6-chloro-) is used as PROTAC linker.
T5102 TGN-020 51987-99-6 99.54%
TGN-020
TGN-020 is an inhibitor of Aquaporin 4 (AQP4, IC50: 3.1 μM), the most abundant water channel in the brain.
T17668 Boc-NH-PEG12-NH2 1642551-09-4 99.52%
Boc-NH-PEG12-NH2
Boc-NH-PEG12-NH2 (NHBoc-PEG12-amine) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
Pomalidomide-PEG3-C2-NH2
T17883
Pomalidomide-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 5) is a synthesized E3 ligase ligand-linker conjugate incorporating the Pomalidomide based cereblon l...
NH2-PEG2-C6-Cl
T40858
NH2-PEG2-C6-Cl is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein d...
NH2-C6-NH-Boc
T18487
NH2-C6-NH-Boc is a PROTAC linker. NH2-C6-NH-Boc can be used in the synthesis the Mcl-1 inhibitor based on PROTAC.
(+)-Biotin-ONP
T18546
(+)-Biotin-ONP ((+)-Biotin 4-nitrophenyl ester) is an alkyl chain-based PROTAC linker. (+)-Biotin-ONP can be used in the synthesis of PROTACs.
NH2-C4-NH-Boc
T18485
NH2-C4-NH-Boc (compound 15) is a PROTAC linker belonging to the Alkyl/ether class. NH2-C4-NH-Boc can be used to synthesize a series of PROTAC molecules.
Acid-C1-PEG5-Boc
T17352
Acid-C1-PEG5-Boc is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
BM-PEG3
T17637
BM-PEG3 (1,11-Bis-maleimidotetraethyleneglycol) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
Boc-NH-PEG4-CH2COOH
T14746
Boc-NH-PEG4-CH2COOH is a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC)[1].
Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD
T16486
Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD (PF-05231023) is a long-acting fibroblast growth factor 21 (FGF21) analog and is an FGF21-receptor agonist. It is also suita...
Ac4GalNAz
T17348
Ac4GalNAz is an alkyl chain-based PROTAC linker that can be used in PROTAC synthesis.
Dinoprost tromethamine salt
T4546
Dinoprost tromethamine salt (PGF2α THAM) is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient.
Amino-PEG12-Boc
T17408
Amino-PEG12-Boc is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
Cbz-NH-PEG1-CH2CH2COOH
T17716
Cbz-NH-PEG1-CH2CH2COOH is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
Biotin-EDA
T17549
Biotin-EDA is an alkyl chain-based PROTAC linker that can be used in PROTAC synthesis.
Boc-11-aminoundecanoic acid
T17638
Boc-11-aminoundecanoic acid is an Alkyl/ether-based PROTAC linker that can be used in the synthesis of MS432.
Aminooxy-PEG4-alcohol
T14271
Aminooxy-PEG4-alcohol is both a non-cleavable 4-unit PEG ADC linker and a PEG-based PROTAC linker.
Fmoc-8-amino-3,6-dioxaoctanoic acid
T15304
Fmoc-8-amino-3,6-dioxaoctanoic acid (Fmoc-NH-PEG2-CH2COOH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It is also a PEG-b...
1-Bromo-6-chlorohexane
T40728
1-Bromo-6-chlorohexane (Hexane, 1-bromo-6-chloro-) is used as PROTAC linker.
TGN-020
T5102
TGN-020 is an inhibitor of Aquaporin 4 (AQP4, IC50: 3.1 μM), the most abundant water channel in the brain.
Boc-NH-PEG12-NH2
T17668
Boc-NH-PEG12-NH2 (NHBoc-PEG12-amine) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
1 2 3 4 5 6 7 8 9
TargetMol