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1,7-Diaminoheptane
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Catalog No. T7998Cas No. 646-19-5
1,7-Diaminoheptane is a compound of the aliphatic amine family. It is used in the synthesis of peptides, peptidomimetics, and other compounds, and has also been used as a substrate in enzyme reactions, as a ligand in metal complexes, and as a reagent in organic synthesis.
1,7-Diaminoheptane
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Purity: 99.97%
Catalog No. T7998Cas No. 646-19-5
1,7-Diaminoheptane is a compound of the aliphatic amine family. It is used in the synthesis of peptides, peptidomimetics, and other compounds, and has also been used as a substrate in enzyme reactions, as a ligand in metal complexes, and as a reagent in organic synthesis.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 200 mg | $29 | Inquiry | Inquiry |
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Batch Information
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Purity:99.97%
Appearance:Liquid
Color:Transparent
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Product Introduction
1,7-Diaminoheptane AI Summary
1,7-Diaminoheptane exhibits a bioactivity of inhibiting recombinant deoxyhypusine synthase in Plasmodium falciparum NF54 with a Ki value of 50000.0 nM. It demonstrates cytotoxicity against mouse J774 macrophage cells at concentrations of 1 μg/mL, 10 μg/mL, and 100 μg/mL, with 100% activity, indicating a strong cytotoxic effect. However, when tested against Mycobacterium bovis Bacillus Calmette-Guérin infected mouse J774 macrophage cells, the compound shows decreased activity, with activity percentages ranging from 70% to 79% across all concentrations, suggesting a reduced cytotoxic effect on infected cells compared to uninfected cells..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | 1,7-Diaminoheptane is a compound of the aliphatic amine family. It is used in the synthesis of peptides, peptidomimetics, and other compounds, and has also been used as a substrate in enzyme reactions, as a ligand in metal complexes, and as a reagent in organic synthesis. |
| Molecular Weight | 130.23 |
| Formula | C7H18N2 |
| Cas No. | 646-19-5 |
| Smiles | C(CCCN)CCCN |
| Relative Density. | 0,86 g/cm3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO: Slightly soluble  |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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