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Anti-BASP1 Antibody (4A217) is a Mouse antibody targeting BASP1. Anti-BASP1 Antibody (4A217) can be used in ELISA.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 μL | $198 | 7-10 days | 7-10 days |
| Description | Anti-BASP1 Antibody (4A217) is a Mouse antibody targeting BASP1. Anti-BASP1 Antibody (4A217) can be used in ELISA. |
| Synonyms | NAP-22, NAP22, CAP-23, CAP23, BASP 1 |
| Ig Type | Mouse IgG2b |
| Clone | 4A217 |
| Reactivity | Human |
| Specificity | Human Brain acid soluble protein 1/BASP1 |
| Application | |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human BASP1 (P80723; aa3-227). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | The AML1-ETO fusion protein (A/E), which results from the t(8;21) translocation, is considered to be a leukemia-initiating event. Identifying the mechanisms underlying the oncogenic activity of A/E remains a major challenge. BASP1 silencing via promoter methylation may be involved in A/E-mediated leukemogenesis and that BASP1 targeting may be an actionable therapeutic strategy in t(8;21) AML. BASP1 is a novel prognostic factor for patients with cervical cancer, and promotes the proliferation and tumorigenicity of cervical cancer. BASP1 acts as a major selectivity factor in the transcriptional response of breast cancer cells to tamoxifen. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human BASP1 Protein |
| Antigen Species | Human |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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