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Dickkopf-1 (Dkk1), the founding and best-studied member of the Dkk family, functions as an antagonist of canonical Wnt/β-catenin. Dkk1 is considered to play a broad role in a variety of biological processes. DKK1 N terminal Domain Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 40.25 kDa and the accession number is O94907.

| Pack Size | Price | Availability | Quantity | 
|---|---|---|---|
| 5 μg | $91 | 7-10 days | |
| 10 μg | $148 | 7-10 days | |
| 20 μg | $245 | 7-10 days | |
| 50 μg | $483 | 7-10 days | |
| 100 μg | $813 | 7-10 days | |
| 200 μg | $1,470 | 7-10 days | |
| 500 μg | $3,250 | 7-10 days | 
| Biological Activity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. | 
| Description | Dickkopf-1 (Dkk1), the founding and best-studied member of the Dkk family, functions as an antagonist of canonical Wnt/β-catenin. Dkk1 is considered to play a broad role in a variety of biological processes. DKK1 N terminal Domain Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 40.25 kDa and the accession number is O94907. | 
| Species | Human | 
| Expression System | HEK293 Cells | 
| Tag | C-hFc-Avi | 
| Accession Number | O94907 | 
| Synonyms | SK,hDkk-1,hDkk1,Dkk-1,Dkk1,Dickkopf-related 1,Dickkopf-1 | 
| Construction | Thr32-Asp142 | 
| Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC | 
| Molecular Weight | 40.25 kDa (predicted). Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result. | 
| Endotoxin | < 1 EU/μg by the LAL method. | 
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. | 
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. | 
| Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. | 
| Shipping | In general, Lyophilized powders are shipping with blue ice. | 
| Research Background | Dickkopf-1 (Dkk1), the founding and best-studied member of the Dkk family, functions as an antagonist of canonical Wnt/β-catenin. Dkk1 is considered to play a broad role in a variety of biological processes. | 

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