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1-(2,3-DIHYDRO-BENZO[1,4]DIOXIN-6-YL)-5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID

🥰Excellent
Catalog No. T8913Cas No. 260555-42-8

1-(2,3-DIHYDRO-BENZO[1,4]DIOXIN-6-YL)-5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID targets GRK2.

1-(2,3-DIHYDRO-BENZO[1,4]DIOXIN-6-YL)-5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID

1-(2,3-DIHYDRO-BENZO[1,4]DIOXIN-6-YL)-5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID

🥰Excellent
Purity: 99.55%
Catalog No. T8913Cas No. 260555-42-8
1-(2,3-DIHYDRO-BENZO[1,4]DIOXIN-6-YL)-5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID targets GRK2.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
10 mg$31In StockIn Stock
25 mg$54In StockIn Stock
50 mg$81In StockIn Stock
100 mg$120In StockIn Stock
200 mg$181-In Stock
1 mL x 10 mM (in DMSO)$29In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.55%
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COA HNMR LCMS HPLC

Product Introduction

Bioactivity
Description
1-(2,3-DIHYDRO-BENZO[1,4]DIOXIN-6-YL)-5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID targets GRK2.
Chemical Properties
Molecular Weight263.25
FormulaC13H13NO5
Cas No.260555-42-8
SmilesOC(=O)C1CN(C(=O)C1)C1=CC2=C(OCCO2)C=C1
Relative Density.1.449 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 22.5 mg/mL (85.47 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.7987 mL18.9934 mL37.9867 mL189.9335 mL
5 mM0.7597 mL3.7987 mL7.5973 mL37.9867 mL
10 mM0.3799 mL1.8993 mL3.7987 mL18.9934 mL
20 mM0.1899 mL0.9497 mL1.8993 mL9.4967 mL
50 mM0.0760 mL0.3799 mL0.7597 mL3.7987 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Tech Support

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Keywords

GRK21(2,3DIHYDROBENZO[1,4]DIOXIN6YL)5OXOPYRROLIDINE3CARBOXYLIC ACID1 (2,3 DIHYDRO BENZO[1,4]DIOXIN 6 YL) 5 OXO PYRROLIDINE 3 CARBOXYLIC ACID
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