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Anti-Phospho-IKK- gamma (Ser85) Polyclonal Antibody
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Catalog No. TMAC-02133
Anti-Phospho-IKK- gamma (Ser85) Polyclonal Antibody is a Rabbit antibody targeting Phospho-IKK- gamma (Ser85). Anti-Phospho-IKK- gamma (Ser85) Polyclonal Antibody can be used in WB.
Anti-Phospho-IKK- gamma (Ser85) Polyclonal Antibody
Anti-Phospho-IKK- gamma (Ser85) Polyclonal Antibody
😃Good
Catalog No. TMAC-02133
Anti-Phospho-IKK- gamma (Ser85) Polyclonal Antibody is a Rabbit antibody targeting Phospho-IKK- gamma (Ser85). Anti-Phospho-IKK- gamma (Ser85) Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $217 | 7-10 days | |
| 100 μL | $317 | 7-10 days |
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| Description | Anti-Phospho-IKK- gamma (Ser85) Polyclonal Antibody is a Rabbit antibody targeting Phospho-IKK- gamma (Ser85). Anti-Phospho-IKK- gamma (Ser85) Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse |
| Application | |
| Recommended Dose | WB: 1:500-1000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. However, the specific type of polyubiquitin recognized upon cell stimulation (either 'Lys-63'-linked or linear polyubiquitin) and its functional importance is reported conflictingly. Also considered to be a mediator for TAX activation of NF-kappa-B. Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity. Essential for viral activation of IRF3. Involved in TLR3- and IFIH1-mediated antiviral innate response; this function requires 'Lys-27'-linked polyubiquitination. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of serine 85 (Q-A-S(p)-Q-R) derived from Human IKK-gamma |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 48 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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