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Cadherin 17/CDH17 Domain 7 Protein, Human, Recombinant (hFc)

(Synonyms: P130, MGC142024, MGC138218, LI-cadherin, HPT-1, FLJ26931, Cdh17, CDH16, Cadherin-17, cadherin-16, BILL-cadherin) Copy Product Info

Synonyms: P130, MGC142024, MGC138218, LI-cadherin, HPT-1, FLJ26931, Cdh17, CDH16, Cadherin-17, cadherin-16, BILL-cadherin

Catalog No. TMPK-00949 Copy Product Info
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Domain 7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 38.42 kDa and the accession number is Q12864.
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$707-10 days7-10 days
10 μg$1127-10 days7-10 days
20 μg$1837-10 days7-10 days
50 μg$3587-10 days7-10 days
100 μg$6057-10 days7-10 days
200 μg$1,0907-10 days7-10 days
500 μg$2,4207-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Domain 7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 38.42 kDa and the accession number is Q12864.
Species
Human
Expression System
HEK293 Cells
TagC-hFc
Accession NumberQ12864
ConstructionAla668-Gly777
Protein Purity
> 95% as determined by Tris-Bis PAGE
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationSupplied as 0.22 μm filtered solution in 20 mM Tris, 150 mM NaCl (pH 8.0).
Stability & StorageIt is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingProteins are shipped with blue ice.
SynonymsP130, MGC142024, MGC138218, LI-cadherin, HPT-1, FLJ26931, Cdh17, CDH16, Cadherin-17, cadherin-16, BILL-cadherin
Research Background
Chemical Properties
Molecular Weight38.42 kDa (predicted). Due to glycosylation, the protein migrates to 48-52 kDa based on Tris-Bis PAGE result.
Storage & Solubility Information
StorageStore at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Keywords

Related Tags: Cadherin 17/CDH17 Domain 7 Protein, Human, Recombinant (hFc) chemical structure | Cadherin 17/CDH17 Domain 7 Protein, Human, Recombinant (hFc) molecular weight