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Cadherin 17/CDH17 Domain 7 Protein, Human, Recombinant (hFc)
(Synonyms: P130, MGC142024, MGC138218, LI-cadherin, HPT-1, FLJ26931, Cdh17, CDH16, Cadherin-17, cadherin-16, BILL-cadherin) Copy Product InfoSynonyms: P130, MGC142024, MGC138218, LI-cadherin, HPT-1, FLJ26931, Cdh17, CDH16, Cadherin-17, cadherin-16, BILL-cadherin
Catalog No. TMPK-00949 Copy Product Info
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Domain 7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 38.42 kDa and the accession number is Q12864.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 µg | $112 | 7-10 days | 7-10 days | |
| 20 µg | $183 | 7-10 days | 7-10 days | |
| 50 µg | $358 | 7-10 days | 7-10 days | |
| 100 µg | $605 | 7-10 days | 7-10 days | |
| 200 µg | $1,090 | 7-10 days | 7-10 days | |
| 500 µg | $2,420 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Immobilized Human CDH17 Domain 7, hFc Tag at 1 μg/mL (100 μL/well) on the plate. Dose response curve for Biotinylated Anti-CDH17 Domain 7 Antibody, hFc Avi Tag with the EC50 of 15.0 ng/mL determined by ELISA.(QC Test) |
| Description | Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Domain 7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 38.42 kDa and the accession number is Q12864. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-hFc |
| Accession Number | Q12864 |
| Construction | Ala668-Gly777 |
| Protein Purity | > 95% as determined by Tris-Bis PAGE |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Supplied as 0.22 μm filtered solution in 20 mM Tris, 150 mM NaCl (pH 8.0). |
| Synonyms | P130, MGC142024, MGC138218, LI-cadherin, HPT-1, FLJ26931, Cdh17, CDH16, Cadherin-17, cadherin-16, BILL-cadherin |
| Research Background | Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. |
| Molecular Weight | 38.42 kDa (predicted). Due to glycosylation, the protein migrates to 48-52 kDa based on Tris-Bis PAGE result. |
| Shipping | Proteins are shipped with blue ice. |
| Storage | It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: Cadherin 17/CDH17 Domain 7 Protein, Human, Recombinant (hFc) chemical structure | Cadherin 17/CDH17 Domain 7 Protein, Human, Recombinant (hFc) molecular weight
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