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IL-15RA Protein, Human, Recombinant (hFc, Human Cells)
(Synonyms: α, MGC104179, interleukin-15 receptor subunit α, interleukin-15 receptor subunit alpha, interleukin 15 receptor, IL-15R-α, IL-15R-alpha, IL-15RA, IL15RA, IL-15 receptor subunit α, IL-15 receptor subunit alpha, CD215 antigen, CD215, alpha) Copy Product InfoSynonyms: α, MGC104179, interleukin-15 receptor subunit α, interleukin-15 receptor subunit alpha, interleukin 15 receptor, IL-15R-α, IL-15R-alpha, IL-15RA, IL15RA, IL-15 receptor subunit α, IL-15 receptor subunit alpha, CD215 antigen, CD215, alpha
Catalog No. TMPJ-01099 Copy Product Info
Purity: 99.15%
Interleukin 15 Receptor alpha (IL-15Rα) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Rα chain can bind soluble IL-15 and "transpresent" cytokine to the cells, allowing them to respond to IL-15. Soluble IL-15Rα can function as a specific high-affinity IL-15 antagonist. The soluble IL-15/IL-15Rα complexes exhibit a strong agonistic activity which is mediated through membrane-bound IL-15 receptor β and γ heterodimers and enables signaling to cells.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $74 | 7-10 days | 7-10 days | |
| 10 μg | $118 | - | In Stock | |
| 20 μg | $190 | 7-10 days | 7-10 days | |
| 50 μg | $350 | 7-10 days | 7-10 days | |
| 100 μg | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.15%
Appearance:Lyophilized powder
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Measured by its ability to block human IL-15-induced proliferation of CTLL‑2 mouse cytotoxic T cells. The ED50 for this effect is 0.35-3.5 ng/ml. (QC verified)  |
| Description | Interleukin 15 Receptor alpha (IL-15Rα) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Rα chain can bind soluble IL-15 and "transpresent" cytokine to the cells, allowing them to respond to IL-15. Soluble IL-15Rα can function as a specific high-affinity IL-15 antagonist. The soluble IL-15/IL-15Rα complexes exhibit a strong agonistic activity which is mediated through membrane-bound IL-15 receptor β and γ heterodimers and enables signaling to cells. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-hFc |
| Accession Number | Q13261-3 |
| Amino Acid | Ile31-Thr172 |
| Construction | Ile31-Thr172 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. Greater than 95% as determined by SEC-HPLC.   |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 150 mM NaCl, pH 7.4. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | α, MGC104179, interleukin-15 receptor subunit α, interleukin-15 receptor subunit alpha, interleukin 15 receptor, IL-15R-α, IL-15R-alpha, IL-15RA, IL15RA, IL-15 receptor subunit α, IL-15 receptor subunit alpha, CD215 antigen, CD215, alpha |
| Research Background |
| Molecular Weight | 60-75 KDa (reducing condition) |
| Storage | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Related Tags: IL-15RA Protein, Human, Recombinant (hFc, Human Cells) chemical structure | IL-15RA Protein, Human, Recombinant (hFc, Human Cells) molecular weight
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