Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DNA-PK-IN-10 is a DNA-PK inhibitor utilized in the research of breast cancer and non-small cell lung cancer [1].
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5 mg | Inquiry | Inquiry | |
50 mg | Inquiry | Inquiry |
Description | DNA-PK-IN-10 is a DNA-PK inhibitor utilized in the research of breast cancer and non-small cell lung cancer [1]. |
In vitro | DNA-PK-IN-10 (Example 31) inhibits the viability of MDA-MB-468 cells with an IC50 value of 11.2 nM [1]. |
In vivo | DNA-PK-IN-10 (Example 31) administered at 30mg/kg twice daily significantly inhibited tumor growth and demonstrated good tolerability in mice inoculated with NCI-H1703 cells [1]. |
Molecular Weight | 444.53 |
Formula | C25H28N6O2 |
CAS No. | 2919315-89-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
DNA-PK-IN-10 2919315-89-0 DNA Damage/DNA Repair PI3K/Akt/mTOR signaling DNA-PK inhibitor inhibit