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Anti-Phospho-TOP2A (Ser1469) Polyclonal Antibody (Synonyms: TOP2A (p-Ser1469), TOP2A (p-S1469), p-TOP2A (Ser14...)

Catalog No. TMAC-04088 Copy Product Info
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Anti-Phospho-TOP2A (Ser1469) Polyclonal Antibody is a Rabbit antibody targeting Phospho-TOP2A (Ser1469). Anti-Phospho-TOP2A (Ser1469) Polyclonal Antibody can be used in WB.

Anti-Phospho-TOP2A (Ser1469) Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAC-04088
Synonyms TOP2A (p-Ser1469), TOP2A (p-S1469), p-TOP2A (Ser1469), p-TOP2A (S1469)

Anti-Phospho-TOP2A (Ser1469) Polyclonal Antibody is a Rabbit antibody targeting Phospho-TOP2A (Ser1469). Anti-Phospho-TOP2A (Ser1469) Polyclonal Antibody can be used in WB.

Anti-Phospho-TOP2A
(Ser1469) Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2187-10 days7-10 days
100 μL$3177-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-TOP2A (Ser1469) Polyclonal Antibody is a Rabbit antibody targeting Phospho-TOP2A (Ser1469). Anti-Phospho-TOP2A (Ser1469) Polyclonal Antibody can be used in WB.
SynonymsTOP2A (p-Ser1469), TOP2A (p-S1469), p-TOP2A (Ser1469), p-TOP2A (S1469)
Ig Type
IgG
Reactivity
Human
Application
Recommended Dose
WB: 1:1000-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
AppearanceLiquid
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Research Backgroundtopoisomerase (DNA) II alpha(TOP2A) Homo sapiens This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, alpha, is localized to chromosome 17 and the beta gene is localized to chromosome 3. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also pla
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
A synthesized phosphopeptide: human Topoisomerase IIα around the phosphorylation site of Ser1469
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 174 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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