TSLP Protein, Human, Recombinant (hFc)

Name: TSLP Protein, Human, Recombinant (hFc)
Brand: TargetMol
SKU: TMPY-06505
Rating: 4.5 (1 reviews)

(Synonyms: thymic stromal lymphopoietin) Copy Product Info

Synonyms: thymic stromal lymphopoietin

Catalog No. TMPY-06505 Copy Product Info

TSLP Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.50 kDa and the accession number is NP_149024.1.

Pack Size	Price	USA Stock	Global Stock
5 µg	$55	7-10 days	7-10 days
10 µg	$87	7-10 days	7-10 days
20 µg	$142	7-10 days	7-10 days
50 µg	$277	7-10 days	7-10 days
100 µg	$535	7-10 days	7-10 days
200 µg	$855	7-10 days	7-10 days
500 µg	$2,320	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Immobilized Recombinant Human CRLF2 Protein (His Tag) at 2 μg/mL (100 μL/well) can bind Recombinant Human TSLP Protein (R127A, R130S, Fc Tag), the EC50 is 1.5-4.0 ng/mL.
Description	TSLP Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.50 kDa and the accession number is NP_149024.1.
Species	Human
Expression System	HEK293 Cells
Tag	C-hFc
Accession Number	NP_149024.1
Construction	A DNA sequence encoding the Human TSLP (NP_149024.1) (R127A, R130S, Met1-Gln159) was expressed with the fused Fc region of human IgG1 at the C-terminus. Predicted N terminal: Tyr 29
Protein Purity	> 95 % as determined by SDS-PAGE.
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Synonyms	thymic stromal lymphopoietin
Research Background	Thymic stromal lymphopoietin (TSLP) is an interleukin 7 (IL-7)-like cytokine originally characterized by its ability to promote the activation of B cells and dendritic cells (DCs). Thymic stromal lymphopoietin (TSLP) is a cytokine expressed by epithelial cells, including keratinocytes, and is important in allergic inflammation. Subsequent studies have shown that TSLP promotes T helper type 2 (TH2) cell responses associated with immunity to some helminth parasites and the pathogenesis of many inflammatory diseases, including atopic dermatitis and asthma. TSLP can promote TH2 cytokine-associated inflammation by directly promoting the effector functions of CD4+TH2 cells, basophils and other granulocyte populations while simultaneously limiting the expression of DC-derived proinflammatory cytokines and promoting regulatory T cell responses in peripheral tissues.

Chemical Properties

Molecular Weight

41.50 kDa (predicted); 46.22 kDa (reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.