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Oxantel Pamoate

Name: Oxantel Pamoate
Brand: TargetMol
SKU: T0323
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T0323Cas No. 68813-55-8

Alias Oxantel embonate

Oxantel Pamoate (Oxantel embonate) is used as an Antinematodal agent.

Oxantel Pamoate

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Purity: 99.89%

Catalog No. T0323Alias Oxantel embonateCas No. 68813-55-8

Oxantel Pamoate (Oxantel embonate) is used as an Antinematodal agent.

Pack Size	Price	USA Warehouse	Global Warehouse
200 mg	$31	In Stock	In Stock
500 mg	$48	In Stock	In Stock
1 g	$70	-	In Stock
5 g	$168	-	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.89%

Color:Yellow

Resource Download

COA HPLC HNMR LCMS

Product Introduction

Bioactivity

Description	Oxantel Pamoate (Oxantel embonate) is used as an Antinematodal agent.
In vivo	The efficacy of the veterinary drug Oxantel pamoate against Trichuris muris, Ancylostoma ceylanicum, and Necator americanus was evaluated, revealing an ED50s of 4.7 mg/kg for T. muris in mice. When combined with pyrantel pamoate, Oxantel pamoate showed an antagonistic interaction (CI=2.53). Similarly, combinations with Levamisole, Albendazole, or Ivermectin, based on their ED50s, also demonstrated antagonistic effects (CIs of 1.27, 1.90, and 1.27, respectively). Conversely, a combination with mebendazole exhibited a highly synergistic effect (CI=0.15) against T. muris infection. At a dosage of 10 mg/kg, Oxantel pamoate was ineffective against A. ceylanicum and N. americanus[1].
Synonyms	Oxantel embonate

Chemical Properties

Molecular Weight	604.65
Formula	C₃₆H₃₂N₂O₇
Cas No.	68813-55-8
Smiles	CN1CCCN=C1\C=C\c1cccc(O)c1.OC(=O)c1cc2ccccc2c(Cc2c(O)c(cc3ccccc23)C(O)=O)c1O
Relative Density.	1.09 g/cm3

Storage & Solubility Information

Storage

In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (99.23 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (3.31 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.6538 mL	8.2692 mL	16.5385 mL	82.6925 mL
5 mM	0.3308 mL	1.6538 mL	3.3077 mL	16.5385 mL
10 mM	0.1654 mL	0.8269 mL	1.6538 mL	8.2692 mL
20 mM	0.0827 mL	0.4135 mL	0.8269 mL	4.1346 mL
50 mM	0.0331 mL	0.1654 mL	0.3308 mL	1.6538 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc