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Oxantel Pamoate (Oxantel embonate) is used as an Antinematodal agent.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 200 mg | $31 | In Stock | In Stock | |
| 500 mg | $48 | In Stock | In Stock | |
| 1 g | $70 | - | In Stock | |
| 5 g | $168 | - | In Stock | |
| 1 mL x 10 mM (in DMSO) | $29 | In Stock | In Stock |
| Description | Oxantel Pamoate (Oxantel embonate) is used as an Antinematodal agent. |
| In vivo | The efficacy of the veterinary drug Oxantel pamoate against Trichuris muris, Ancylostoma ceylanicum, and Necator americanus was evaluated, revealing an ED50s of 4.7 mg/kg for T. muris in mice. When combined with pyrantel pamoate, Oxantel pamoate showed an antagonistic interaction (CI=2.53). Similarly, combinations with Levamisole, Albendazole, or Ivermectin, based on their ED50s, also demonstrated antagonistic effects (CIs of 1.27, 1.90, and 1.27, respectively). Conversely, a combination with mebendazole exhibited a highly synergistic effect (CI=0.15) against T. muris infection. At a dosage of 10 mg/kg, Oxantel pamoate was ineffective against A. ceylanicum and N. americanus[1]. |
| Synonyms | Oxantel embonate |
| Molecular Weight | 604.65 |
| Formula | C36H32N2O7 |
| Cas No. | 68813-55-8 |
| Smiles | CN1CCCN=C1\C=C\c1cccc(O)c1.OC(=O)c1cc2ccccc2c(Cc2c(O)c(cc3ccccc23)C(O)=O)c1O |
| Relative Density. | 1.09 g/cm3 |
| Color | Yellow |
| Appearance | Solid |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 60 mg/mL (99.23 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||
| In Vivo Formulation | 10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (3.31 mM), Sonication is recommended. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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