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Ospemifene

🥰Excellent
Catalog No. T6620Cas No. 128607-22-7
Alias FC-1271a

Ospemifene (FC-1271a) is a new selective non-hormonal estrogen receptor modulator (SERM) that is used for the treatment of moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy, due to menopause. FDA approved on February 26, 2013.

Ospemifene
Other Forms of Ospemifene:
Ospemifene D4T12329
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Ospemifene

🥰Excellent
Purity: 99.95%
Catalog No. T6620Alias FC-1271aCas No. 128607-22-7
Ospemifene (FC-1271a) is a new selective non-hormonal estrogen receptor modulator (SERM) that is used for the treatment of moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy, due to menopause. FDA approved on February 26, 2013.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
10 mg$30In StockIn Stock
25 mg$37In StockIn Stock
50 mg$52In StockIn Stock
100 mg$75In StockIn Stock
500 mg$182In Stock-
1 mL x 10 mM (in DMSO)$30In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Purity:99.95%
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COA HNMR LCMS HPLC

Product Introduction

Bioactivity
Description
Ospemifene (FC-1271a) is a new selective non-hormonal estrogen receptor modulator (SERM) that is used for the treatment of moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy, due to menopause. FDA approved on February 26, 2013.
Targets&IC50
ERα:827nM, ERβ:1633nM
SynonymsFC-1271a
Chemical Properties
Molecular Weight378.89
FormulaC24H23ClO2
Cas No.128607-22-7
SmilesOCCOc1ccc(cc1)C(=C(CCCl)c1ccccc1)c1ccccc1
Relative Density.1.166g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 55 mg/mL (145.16 mM), Sonication is recommended.
Ethanol: 66 mg/mL (174.19 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (5.28 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO/Ethanol
1mg5mg10mg50mg
1 mM2.6393 mL13.1964 mL26.3929 mL131.9644 mL
5 mM0.5279 mL2.6393 mL5.2786 mL26.3929 mL
10 mM0.2639 mL1.3196 mL2.6393 mL13.1964 mL
20 mM0.1320 mL0.6598 mL1.3196 mL6.5982 mL
50 mM0.0528 mL0.2639 mL0.5279 mL2.6393 mL
100 mM0.0264 mL0.1320 mL0.2639 mL1.3196 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

progestogenReceptorprogestogen ReceptorOspemifeneInhibitorinhibitEstrogenReceptorEstrogen Receptor/ERREstrogen ReceptorERRER
Related Tags: buy Ospemifene | purchase Ospemifene | Ospemifene cost | order Ospemifene | Ospemifene chemical structure | Ospemifene formula | Ospemifene molecular weight
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