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Anti-gp130/IL6ST Antibody (4O20) (Synonyms: interleukin 6 signal transducer, IL-6RB, GP130, CDW130, CD130)

Catalog No. TMAY-01390 Copy Product Info
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Anti-gp130/IL6ST Antibody (4O20) is a Rabbit antibody targeting gp130/IL6ST. Anti-gp130/IL6ST Antibody (4O20) can be used in ELISA.

Anti-gp130/IL6ST Antibody (4O20)

Copy Product Info
🥰Excellent
Catalog No. TMAY-01390
Synonyms interleukin 6 signal transducer, IL-6RB, GP130, CDW130, CD130

Anti-gp130/IL6ST Antibody (4O20) is a Rabbit antibody targeting gp130/IL6ST. Anti-gp130/IL6ST Antibody (4O20) can be used in ELISA.

Anti-gp130/IL6ST Antibody
(4O20)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$2697-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-gp130/IL6ST Antibody (4O20) is a Rabbit antibody targeting gp130/IL6ST. Anti-gp130/IL6ST Antibody (4O20) can be used in ELISA.
Synonymsinterleukin 6 signal transducer, IL-6RB, GP130, CDW130, CD130
Ig Type
Rabbit IgG
Clone
4O20
Reactivity
Human
Specificity
Human gp130/IL6ST
Application
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human IL6ST/gp130/CD130 (rh IL6ST/gp130/CD130; NP_002175.2Met1-Ile618).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundGlycoprotein 130 (also known as gp130, IL6ST, IL6-beta, or CD130) is a transmembrane protein that is the founding member of the class of all cytokine receptors. CD130/gp130 is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and Oncostatin M (OSM). CD130/gp130 functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. CD130/gp130 plays a critical role in regulating myocyte apoptosis. Alternatively, spliced transcript variants encoding distinct isoforms have been described. A related pseudogene has been identified on chromosome 17. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1, and BSF3 can utilize gp130 for initiating signal transmission. CD130/gp130 binds to IL6/IL6R (alpha chain) complex, resulting in the formation of high-affinity IL6 binding sites, and transduces the signal. CD130/gp130 may have a role in embryonic development. The type I OSM receptor is capable of transducing OSM-specific signaling events.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human IL6ST/gp130/CD130 Protein
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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