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Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $31 | 5 days |
Description | Boc-PEG4-C2-NHS ester is a PEG-based linker for PROTACs that joins two essential ligands to form PROTAC molecules, enabling selective protein degradation via the ubiquitin-proteasome system within cells. |
In vitro | PROTACs, comprising two distinct ligands connected by a linker, utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins; one ligand binds to an E3 ubiquitin ligase while the other binds to the target protein [1]. |
Molecular Weight | 447.48 |
Formula | C20H33NO10 |
Cas No. | 1835759-75-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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