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Anti-Phospho-Androgen receptor (Ser650) Polyclonal Antibody 2

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Catalog No. TMAC-00202

Anti-Phospho-Androgen receptor (Ser650) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Androgen receptor (Ser650). Anti-Phospho-Androgen receptor (Ser650) Polyclonal Antibody can be used in WB,IHC.

Anti-Phospho-Androgen receptor (Ser650) Polyclonal Antibody 2

Anti-Phospho-Androgen receptor (Ser650) Polyclonal Antibody 2

😃Good
Catalog No. TMAC-00202
Anti-Phospho-Androgen receptor (Ser650) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Androgen receptor (Ser650). Anti-Phospho-Androgen receptor (Ser650) Polyclonal Antibody can be used in WB,IHC.
Pack SizePriceAvailabilityQuantity
50 μL$2187-10 days
100 μL$3187-10 days
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Product Introduction

Bioactivity
Description
Anti-Phospho-Androgen receptor (Ser650) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Androgen receptor (Ser650). Anti-Phospho-Androgen receptor (Ser650) Polyclonal Antibody can be used in WB,IHC.
Ig Type
IgG
Reactivity
Human
Application
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundThe androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of serine 650 (T-T-S(p)-P-T) derived from Human Androgen Receptor
Antigen Species
human
Uniprot ID
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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