Integrin β-1 (ITGB1) belongs to the integrin β chain family. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. ITGB1 is an integrin unit associated with very late antigen receptors, which contains one VWFA domain. It is known to conjoin with α-3 subunit to create α3β1 complex that reacts to such molecules as netrin-1 and reelin.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 μg | 5 days | $ 138.00 | |
50 μg | 5 days | $ 418.00 | |
500 μg | 5 days | $ 1,950.00 | |
1 mg | 5 days | $ 2,940.00 |
Description | Integrin β-1 (ITGB1) belongs to the integrin β chain family. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. ITGB1 is an integrin unit associated with very late antigen receptors, which contains one VWFA domain. It is known to conjoin with α-3 subunit to create α3β1 complex that reacts to such molecules as netrin-1 and reelin. |
Species | Human |
Expression System | Human Cells |
Tag | C-6His |
Accession Number | P05556 |
Synonyms | Integrin Beta-1, VLA-4 Subunit β, Fibronectin Receptor Subunit Beta, Fibronectin Receptor Subunit β, CD29, ITGB1, Integrin β-1, VLA-4 Subunit Beta, FNRB, MDF2, MSK12 |
Amino Acid | Gln21-Asp728 |
Construction | Recombinant Human Integrin β-1/ITGB1 is produced by our Mammalian expression system and the target gene encoding Gln21-Asp728 is expressed with a 6His tag at the C-terminus. |
Protein Purity | Greater than 90% as determined by reducing SDS-PAGE. Greater than 90% as determined by SEC-HPLC. |
Molecular Weight | 100-130 KDa, reducing conditions |
Endotoxin | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
Reconstitution | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Stability & Storage |
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
Shipping |
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
Research Background | Integrin β-1 (ITGB1) belongs to the integrin β chain family. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. ITGB1 is an integrin unit associated with very late antigen receptors, which contains one VWFA domain. It is known to conjoin with α-3 subunit to create α3β1 complex that reacts to such molecules as netrin-1 and reelin. |
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Please read the User Guide of Recombinant Proteins for more specific information.
ITGB1 Protein, Human, Recombinant (aa 21-728, His) Integrin Beta-1 VLA-4 Subunit β ITGB 1 Integrin b-1 MDF 2 Fibronectin Receptor Subunit Beta Fibronectin Receptor Subunit β MSK-12 CD-29 CD29 ITGB1 Integrin β-1 VLA-4 Subunit Beta MDF-2 CD 29 FNRB MDF2 ITGB-1 MSK12 MSK 12 recombinant recombinant-proteins proteins protein