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RORγ Allosteric Probe-1 (Compound 12h), with excitation and emission wavelengths of 490/524 nm respectively, serves as an allosteric fluorescent probe for investigating RORγ allosteric inhibitors and the function of RORγ [1].

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | Inquiry | Inquiry | |
| 50 mg | Inquiry | Inquiry | Inquiry |
| Description | RORγ Allosteric Probe-1 (Compound 12h), with excitation and emission wavelengths of 490/524 nm respectively, serves as an allosteric fluorescent probe for investigating RORγ allosteric inhibitors and the function of RORγ [1]. |
| In vivo | When incubated with zebrafish for 12 hours, RORγ allosteric probe-1 (1 μM) exhibits fluorescence in the liver and intestines under the green channel, aligning with the reported expression profile of RORγ [1]. |
| Molecular Weight | 1008.37 |
| Formula | C50H37ClF3N5O11S |
| Cas No. | 2983890-50-0 |
| Smiles | O=C1OC2(C=3C1=CC(NC(NCCOCCOCCNC(=O)C=4C=C5C(=CC4)C(=NN5C(=O)C6=C(C(F)(F)F)C=CC=C6Cl)C7=CC=C(C(O)=O)C=C7)=S)=CC3)C=8C(OC=9C2=CC=C(O)C9)=CC(O)=CC8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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