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Anti-Phospho-PPP2CA (Tyr307) Antibody (7S944)
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Catalog No. TMAH-00943
Alias p-PPP2CA (Y307), p-PPP2CA (Tyr307), PPP2CA (p-Y307), PPP2CA (p-Tyr307), Phospho-PPP2CA (Y307)
Anti-Phospho-PPP2CA (Tyr307) Antibody (7S944) is an antibody targeting Phospho-PPP2CA (Tyr307). Anti-Phospho-PPP2CA (Tyr307) Antibody (7S944) can be used in ELISA,WB.
Anti-Phospho-PPP2CA (Tyr307) Antibody (7S944)
Anti-Phospho-PPP2CA (Tyr307) Antibody (7S944)
😃Good
Catalog No. TMAH-00943Alias p-PPP2CA (Y307), p-PPP2CA (Tyr307), PPP2CA (p-Y307), PPP2CA (p-Tyr307), Phospho-PPP2CA (Y307)
Anti-Phospho-PPP2CA (Tyr307) Antibody (7S944) is an antibody targeting Phospho-PPP2CA (Tyr307). Anti-Phospho-PPP2CA (Tyr307) Antibody (7S944) can be used in ELISA,WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $207 | 7-10 days | |
| 100 μL | $349 | 7-10 days |
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Concentration:0.5 mg/mL
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Chemical Properties
| Description | Anti-Phospho-PPP2CA (Tyr307) Antibody (7S944) is an antibody targeting Phospho-PPP2CA (Tyr307). Anti-Phospho-PPP2CA (Tyr307) Antibody (7S944) can be used in ELISA,WB. |
| Synonyms | p-PPP2CA (Y307), p-PPP2CA (Tyr307), PPP2CA (p-Y307), PPP2CA (p-Tyr307), Phospho-PPP2CA (Y307) |
| Ig Type | Rabbit IgG |
| Clone | 7S944 |
| Reactivity | Human |
| Verified Activity | Western Blot -Positive WB detected in A549 whole cell lysate(treated with EGF or not) -All lanes Phospho-PPP2CA antibody at 0.95μg/ml -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 35 KDa -Observed band size: 35 KDa |
| Application | |
| Recommended Dose | WB:1:500-1:5000. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cytoplasm. Nucleus. Chromosome, centromere. Cytoplasm, cytoskeleton, spindle pole. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I. Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'. Mediates dephosphorylation of WEE1, preventing its ubiquitin-mediated proteolysis, increasing WEE1 protein levels, and promoting the G2/M checkpoint. Mediates dephosphorylation of MYC; promoting its ubiquitin-mediated proteolysis: interaction with AMBRA1 enhances interaction between PPP2CA and MYC. Mediates dephosphorylation of FOXO3; promoting its stabilization: interaction with AMBRA1 enhances interaction between PPP2CA and FOXO3. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human Phospho-PPP2CA (Y307) |
| Antigen Species | Human |
| Gene Name | PPP2CA |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Signal Transduction |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Keywords
Serine/threonine-protein phosphatase 2A catalytic subunit α isoformSerine/threonine-protein phosphatase 2A catalytic subunit alpha isoformSerine/threonine-protein phosphatase 2A catalytic subunit a isoformRP-CRPCReplication protein C (RP-C)pPPP2CA (Y307)pPPP2CA (Tyr307)PPP2CA (pY307)PPP2CA (pTyr307)PPP2CA (phospho-Y307)PPP2CA (phospho-Tyr307)PPP2CAPP2A-αPP2AαPP2A-alphaPP2A-a
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