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Anti-SLC7A5 Polyclonal Antibody

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Catalog No. TMAB-01730
Alias y+ system cationic amino acid transporter, Solute carrier family 7 member 5, SLC7A5, MPE16, L-type amino acid transporter 1 (hLAT1), LAT1, Large neutral amino acids transporter small subunit 1, Integral membrane protein E16 (E16), CD98LC, CD98 light chain, 4F2 light chain (4F2 LC;4F2LC)

Anti-SLC7A5 Polyclonal Antibody is a Rabbit antibody targeting SLC7A5. Anti-SLC7A5 Polyclonal Antibody can be used in WB.

Anti-SLC7A5 Polyclonal Antibody

Anti-SLC7A5 Polyclonal Antibody

😃Good
Catalog No. TMAB-01730Alias y+ system cationic amino acid transporter, Solute carrier family 7 member 5, SLC7A5, MPE16, L-type amino acid transporter 1 (hLAT1), LAT1, Large neutral amino acids transporter small subunit 1, Integral membrane protein E16 (E16), CD98LC, CD98 light chain, 4F2 light chain (4F2 LC;4F2LC)
Anti-SLC7A5 Polyclonal Antibody is a Rabbit antibody targeting SLC7A5. Anti-SLC7A5 Polyclonal Antibody can be used in WB.
Pack SizePriceAvailabilityQuantity
50 μL$2227-10 days
100 μL$3747-10 days
200 μL$5297-10 days
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Product Introduction

Bioactivity
Description
Anti-SLC7A5 Polyclonal Antibody is a Rabbit antibody targeting SLC7A5. Anti-SLC7A5 Polyclonal Antibody can be used in WB.
Aliasy+ system cationic amino acid transporter, Solute carrier family 7 member 5, SLC7A5, MPE16, L-type amino acid transporter 1 (hLAT1), LAT1, Large neutral amino acids transporter small subunit 1, Integral membrane protein E16 (E16), CD98LC, CD98 light chain, 4F2 light chain (4F2 LC;4F2LC)
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat)
Verified Activity
Sample: Brain (Rat) Lysate at 40 μg
Primary: Anti-SLC7A5 (TMAB-01730) at 1/300 dilution
Secondary: HRP conjugated Goat-Anti-rabbit IgG (secondary antibody) at 1/5000 dilution
Predicted band size: 55 kDa
Observed band size: 55 kDa
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm, cytosol. Apical cell membrane. Located to the plasma membrane by SLC3A2/4F2hc. Localized to the apical membrane of placental syncytiophoblastic cells. Expressed in both luminal and abluminal membranes of brain capillary endothelial cells.
ConstructionHybridoma Polyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Research BackgroundL-type amino acid transporter 1 (LAT1) is a multipass-membrane protein responsible for sodium-independent, high-affinity transport of large neutral amino acids. LAT1 functions as a disulfide-linked heterodimer with the amino acid transport protein CD98. LAT1 is expressed predominantly in adult lung and liver but is also expressed in brain, thymus, retina, testis, placenta, bone marrow and fetal liver. In the retina, LAT1 localizes to the blood-retinal-barrier (BRB) and mediates L-leucine transport from the blood to the retina. The devastating effects on the brain caused by phenylketonuria are due to the increased levels of LAT1 on the blood-brain-barrier in response to high concentrations of phenylalanine in the blood. LAT1 accepts the amino-acid related anticancer agent melphalan and plays a significant role in cell proliferation, differentiation, and invasion in esophageal squamous cell carcinoma.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human SLC7A5
Antigen Species
Human
Gene ID
Uniprot ID
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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