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2,6-Dimethoxyquinone
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Catalog No. T3739Cas No. 530-55-2
Alias 2,6-Dimethoxy-p-benzoquinone, 2,6-Dimethoxybenzoquinone, 2,6-Dimethoxy-1,4-benzoquinone
2,6-Dimethoxyquinone is a plant derived liposuction inducing factor. It has antilipemic, anticancer, antibacterial, antimalarial and anti-inflammatory properties.
2,6-Dimethoxyquinone
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Purity: 99.51%
Catalog No. T3739Alias 2,6-Dimethoxy-p-benzoquinone, 2,6-Dimethoxybenzoquinone, 2,6-Dimethoxy-1,4-benzoquinoneCas No. 530-55-2
2,6-Dimethoxyquinone is a plant derived liposuction inducing factor. It has antilipemic, anticancer, antibacterial, antimalarial and anti-inflammatory properties.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 200 mg | $29 | In Stock | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information
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Purity:99.51%
Appearance:Solid
Color:White
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Product Introduction
2,6-Dimethoxyquinone AI Summary
2,6-Dimethoxyquinone exhibits a broad range of bioactivities, including cytotoxicity against various human and mouse cell lines. Specifically, it shows cytotoxic activity against human KB cells with an effective dose (ED50) of 3.1 μg/ml and against mouse P388 cells with an effective dose (ED50) of 0.0015 μg/ml. 2,6-Dimethoxyquinone targets numerous cellular processes and pathways, such as the Menin-MLL interaction in leukemias, JMJD2E, and various signaling pathways including ROR gamma and ERK. It has demonstrated inhibitory effects on tumor cell lines from multiple human cancers, such as Renal, Lung, Leukemia, Breast, Ovarian, Melanoma, and Central Nervous System. The compound also exhibits antiviral activity against SARS-CoV-2 with IC50 values greater than 20,000 nM.
Additionally, 2,6-Dimethoxyquinone shows antifeedant and termiticidal activities against Coptotermes formosanus, and inhibits sodium fluorescein uptake in OATP1B1- and OATP1B3-transfected CHO cells. It also displays reactivity with glutathione, suggesting potential implications for cellular redox states. In assays, it has been effective in inhibiting cell proliferation in human RPMI-8226, MM1.S, and MM1.R cells with IC50 values of 10800 nM, 1100 nM, and 3000 nM, respectively..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | 2,6-Dimethoxyquinone is a plant derived liposuction inducing factor. It has antilipemic, anticancer, antibacterial, antimalarial and anti-inflammatory properties. |
| Synonyms | 2,6-Dimethoxy-p-benzoquinone, 2,6-Dimethoxybenzoquinone, 2,6-Dimethoxy-1,4-benzoquinone |
| Molecular Weight | 168.15 |
| Formula | C8H8O4 |
| Cas No. | 530-55-2 |
| Smiles | COC1=CC(=O)C=C(OC)C1=O |
| Relative Density. | 1.3037 g/cm3 (Estimated) |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||
| Solubility Information | DMSO: 1.55 mg/mL (9.22 mM), Sonication is recommended.  | |||||||||||||||
Solution Preparation Table | ||||||||||||||||
DMSO
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Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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