Shopping Cart
- Remove All
Your shopping cart is currently empty
Fobrepodacin
😃Good
Catalog No. T38801Cas No. 1384984-31-9
Alias SPR720, pVXc-486
Fobrepodacin (SPR720) is an orally active and potent phosphate prodrug of SPR719 (VXc-486) with significant in vivo bactericidal activities.
Fobrepodacin
😃Good
Catalog No. T38801Alias SPR720, pVXc-486Cas No. 1384984-31-9
Fobrepodacin (SPR720) is an orally active and potent phosphate prodrug of SPR719 (VXc-486) with significant in vivo bactericidal activities.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 mg | $1,520 | Backorder |
Add to Cart
Add to Quotation
Bulk & Custom
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
View MoreResource Download
Product Introduction
Bioactivity
Chemical Properties
| Description | Fobrepodacin (SPR720) is an orally active and potent phosphate prodrug of SPR719 (VXc-486) with significant in vivo bactericidal activities. |
| In vivo | Fobrepodacin administered through oral gavage at doses of 10, 30, and 100 mg/kg once daily, five days a week for four weeks, significantly reduces the mycobacterial burden in a model of chronic tuberculosis infection in six-week-old female BALB/c and C57BL/6 mice, both uninfected and infected with M. tuberculosis (Erdman). Additionally, a regimen of 100 mg/kg once daily for eight weeks enhances the bactericidal efficacy of antimycobacterial drugs in these models[1]. |
| Synonyms | SPR720, pVXc-486 |
| Molecular Weight | 508.44 |
| Formula | C21H26FN6O6P |
| Cas No. | 1384984-31-9 |
| Relative Density. | 1.496 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Sci Citations
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy Fobrepodacin | purchase Fobrepodacin | Fobrepodacin cost | order Fobrepodacin | Fobrepodacin chemical structure | Fobrepodacin in vivo | Fobrepodacin formula | Fobrepodacin molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.