Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Fobrepodacin (SPR720) is an orally active and potent phosphate prodrug of SPR719 (VXc-486). Fobrepodacin has potent bactericidal activities in vivo.
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25 mg | Inquiry | $ 1,520.00 |
Description | Fobrepodacin (SPR720) is an orally active and potent phosphate prodrug of SPR719 (VXc-486). Fobrepodacin has potent bactericidal activities in vivo. |
In vivo | Fobrepodacin administered through oral gavage at doses of 10, 30, and 100 mg/kg once daily, five days a week for four weeks, significantly reduces the mycobacterial burden in a model of chronic tuberculosis infection in six-week-old female BALB/c and C57BL/6 mice, both uninfected and infected with M. tuberculosis (Erdman). Additionally, a regimen of 100 mg/kg once daily for eight weeks enhances the bactericidal efficacy of antimycobacterial drugs in these models[1]. |
Synonyms | SPR720, pVXc-486 |
Molecular Weight | 508.447 |
Formula | C21H26FN6O6P |
CAS No. | 1384984-31-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Fobrepodacin 1384984-31-9 SPR 720 SPR720 pVXc-486 SPR-720 inhibitor inhibit