Shopping Cart

Your shopping cart is currently empty

Mepivacaine

Name: Mepivacaine
Brand: TargetMol
SKU: T22361
Price: 32 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T22361Cas No. 96-88-8

Alias Carbocaine

Mepivacaine (Carbocaine) is an amide compound for local anaesthesia that causes transient loss of self-consciousness in humans or animals. mepivacaine acts by binding to specific voltage-gated sodium channels in nerve cell membranes, inhibiting sodium inward flow and membrane depolarisation. mepivacaine is indicated for nerve blocks and epidurals.

Mepivacaine

🥰Excellent

Purity: 99.35%

Catalog No. T22361Alias CarbocaineCas No. 96-88-8

Pack Size	Price	USA Warehouse	Global Warehouse
100 mg	$32	-	In Stock
500 mg	$66	-	In Stock
1 g	$94	-	In Stock
1 mL x 10 mM (in DMSO)	$73	-	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:99.35%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	Mepivacaine (Carbocaine) is an amide compound for local anaesthesia that causes transient loss of self-consciousness in humans or animals. mepivacaine acts by binding to specific voltage-gated sodium channels in nerve cell membranes, inhibiting sodium inward flow and membrane depolarisation. mepivacaine is indicated for nerve blocks and epidurals.
In vitro	Mepivacaine exhibits a usage-dependent blockade of Na(v)1.8 channels, while S(-)-bupivacaine shows a preference for TTX-sensitive Na(+) channels.[2]
In vivo	Intratesticular mepivacaine (10 mL ; injection) when compared with intratesticular lidocaine results in improved cremaster muscle relaxation when only waiting five min prior to the start of the procedure.[2]
Synonyms	Carbocaine

Chemical Properties

Molecular Weight	246.35
Formula	C₁₅H₂₂N₂O
Cas No.	96-88-8
Smiles	CN1CCCCC1C(=O)NC1=C(C)C=CC=C1C
Relative Density.	1.077 g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 65 mg/mL (263.85 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.0593 mL	20.2963 mL	40.5927 mL	202.9633 mL
5 mM	0.8119 mL	4.0593 mL	8.1185 mL	40.5927 mL
10 mM	0.4059 mL	2.0296 mL	4.0593 mL	20.2963 mL
20 mM	0.2030 mL	1.0148 mL	2.0296 mL	10.1482 mL
50 mM	0.0812 mL	0.4059 mL	0.8119 mL	4.0593 mL
100 mM	0.0406 mL	0.2030 mL	0.4059 mL	2.0296 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc