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Anti-PTBP1 Antibody (4Z327) (Synonyms: PTBP 1, PTB, Polypyrimidine tract-binding protein 1, hnRNP I, Heterog...)

Catalog No. TMAC-03455 Copy Product Info
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Anti-PTBP1 Antibody (4Z327) is a Rabbit antibody targeting PTBP1. Anti-PTBP1 Antibody (4Z327) can be used in IHC,WB.

Anti-PTBP1 Antibody (4Z327)

Copy Product Info
🥰Excellent
Catalog No. TMAC-03455
Synonyms PTBP 1, PTB, Polypyrimidine tract-binding protein 1, hnRNP I, Heterogeneous nuclear ribonucleoprotein I, 57 kDa RNA-binding protein PPTB-1

Anti-PTBP1 Antibody (4Z327) is a Rabbit antibody targeting PTBP1. Anti-PTBP1 Antibody (4Z327) can be used in IHC,WB.

Anti-PTBP1 Antibody
(4Z327)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2977-10 days7-10 days
100 μL$4977-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-PTBP1 Antibody (4Z327) is a Rabbit antibody targeting PTBP1. Anti-PTBP1 Antibody (4Z327) can be used in IHC,WB.
SynonymsPTBP 1, PTB, Polypyrimidine tract-binding protein 1, hnRNP I, Heterogeneous nuclear ribonucleoprotein I, 57 kDa RNA-binding protein PPTB-1
Ig Type
IgG
Clone
4Z327
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of PTBP1 on different lysates using anti-PTBP1 antibody at 1/500 dilution. Positive control: Lane 1: K562, Lane 2: Jurkat, Lane 3: Mouse colon tissue.
2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-PTBP1 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human skin tissue using anti-PTBP1 antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-PTBP1 antibody. Counter stained with hematoxylin.
5. Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-PTBP1 antibody. Counter stained with hematoxylin.
verifiedActivityverifiedActivityverifiedActivityverifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:500-2000; IHC: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundPlays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10. In case of infection by picornaviruses, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 57 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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