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Anti-PTBP1 Antibody (4Z327)
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Catalog No. TMAC-03455
Alias PTBP 1, PTB, Polypyrimidine tract-binding protein 1, hnRNP I, Heterogeneous nuclear ribonucleoprotein I, 57 kDa RNA-binding protein PPTB-1
Anti-PTBP1 Antibody (4Z327) is a Rabbit antibody targeting PTBP1. Anti-PTBP1 Antibody (4Z327) can be used in WB,IHC.
Anti-PTBP1 Antibody (4Z327)
Anti-PTBP1 Antibody (4Z327)
😃Good
Catalog No. TMAC-03455Alias PTBP 1, PTB, Polypyrimidine tract-binding protein 1, hnRNP I, Heterogeneous nuclear ribonucleoprotein I, 57 kDa RNA-binding protein PPTB-1
Anti-PTBP1 Antibody (4Z327) is a Rabbit antibody targeting PTBP1. Anti-PTBP1 Antibody (4Z327) can be used in WB,IHC.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $297 | 7-10 days | |
| 100 μL | $497 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-PTBP1 Antibody (4Z327) is a Rabbit antibody targeting PTBP1. Anti-PTBP1 Antibody (4Z327) can be used in WB,IHC. |
| Synonyms | PTBP 1, PTB, Polypyrimidine tract-binding protein 1, hnRNP I, Heterogeneous nuclear ribonucleoprotein I, 57 kDa RNA-binding protein PPTB-1 |
| Ig Type | IgG |
| Clone | 4Z327 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of PTBP1 on different lysates using anti-PTBP1 antibody at 1/500 dilution. Positive control: Lane 1: K562, Lane 2: Jurkat, Lane 3: Mouse colon tissue. 2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-PTBP1 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human skin tissue using anti-PTBP1 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-PTBP1 antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-PTBP1 antibody. Counter stained with hematoxylin. |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10. In case of infection by picornaviruses, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 57 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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