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Anti-SMPDL3A Antibody (9P822)

😃Good
Catalog No. TMAY-02605
Alias sphingomyelin phosphodiesterase, acid-like 3A, ASML3A, ASML3, ASM3A, AI529588, 0610010C24Rik

Anti-SMPDL3A Antibody (9P822) is a Rabbit antibody targeting SMPDL3A. Anti-SMPDL3A Antibody (9P822) can be used in ELISA.

Anti-SMPDL3A Antibody (9P822)

Anti-SMPDL3A Antibody (9P822)

😃Good
Catalog No. TMAY-02605Alias sphingomyelin phosphodiesterase, acid-like 3A, ASML3A, ASML3, ASM3A, AI529588, 0610010C24Rik
Anti-SMPDL3A Antibody (9P822) is a Rabbit antibody targeting SMPDL3A. Anti-SMPDL3A Antibody (9P822) can be used in ELISA.
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100 μL$269 7-10 days
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Product Introduction

Bioactivity
Description
Antibody Type: Rabbit Monoclonal

Application: ELISA

Reactivity: Human
Aliassphingomyelin phosphodiesterase, acid-like 3A, ASML3A, ASML3, ASM3A, AI529588, 0610010C24Rik
Ig Type
Rabbit IgG
Clone
9P822
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human SMPDL3A (rh SMPDL3A; TMPY-03278; Q92484; Met1-Tyr453).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundSMPDL3A gene is a novel liver X receptor (LXR) -regulated gene, with an LXR response element within its promoter. The induction of SMPDL3A is LXR-dependent and is restricted to human blood cells with no induction observed in mouse cellular systems. LXR α and LXRβ function as physiological sensors of cholesterol metabolites (oxysterols), regulating key genes involved in cholesterol and lipid metabolism. LXRs have been extensively studied in both human and rodent cell systems, revealing their potential therapeutic value in the contexts of atherosclerosis and inflammatory diseases. The LXR genome landscape has been investigated in murine macrophages but not in human THP-1 cells, which represent one of the frequently used monocyte/macrophage cell systems to study immune responses.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human SMPDL3A protein (TMPY-03278)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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