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Anti-CPT1A Polyclonal Antibody (Synonyms: CPTI-L, CPT1-L, CPT1A, CPT I, CPT 1, Carnitine palmitoyltransfera...)
Catalog No. TMAB-00474 Copy Product Info
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Anti-CPT1A Polyclonal Antibody is a Rabbit antibody targeting CPT1A. Anti-CPT1A Polyclonal Antibody can be used in ICC/IF, IF, IHC-Fr, IHC-P.
Anti-CPT1A Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-00474
Synonyms CPTI-L, CPT1-L, CPT1A, CPT I, CPT 1, Carnitine palmitoyltransferase 1A, carnitine palmitoyl transferase 1, Carnitine O-palmitoyltransferase 1, liver isoform
Anti-CPT1A Polyclonal Antibody is a Rabbit antibody targeting CPT1A. Anti-CPT1A Polyclonal Antibody can be used in ICC/IF, IF, IHC-Fr, IHC-P.
Anti-CPT1A Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-CPT1A Polyclonal Antibody is a Rabbit antibody targeting CPT1A. Anti-CPT1A Polyclonal Antibody can be used in ICC/IF, IF, IHC-Fr, IHC-P. |
| Synonyms | CPTI-L, CPT1-L, CPT1A, CPT I, CPT 1, Carnitine palmitoyltransferase 1A, carnitine palmitoyl transferase 1, Carnitine O-palmitoyltransferase 1, liver isoform |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Paraformaldehyde-fixed, paraffin embedded Rat Colon; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CPT1A Polyclonal Antibody, Unconjugated (TMAB-00474) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining. 2. Paraformaldehyde-fixed, paraffin embedded Mouse Colon; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CPT1A Polyclonal Antibody, Unconjugated (TMAB-00474) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining. 3. Paraformaldehyde-fixed, paraffin embedded Human Colon; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CPT1A Polyclonal Antibody, Unconjugated (TMAB-00474) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining. 4. Paraformaldehyde-fixed, paraffin embedded Human Liver; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CPT1A Polyclonal Antibody, Unconjugated (TMAB-00474) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining. 5. Paraformaldehyde-fixed, paraffin embedded Human Kidney; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CPT1A Polyclonal Antibody, Unconjugated (TMAB-00474) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining. 6. Paraformaldehyde-fixed, paraffin embedded Human Ovarian Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CPT1A Polyclonal Antibody, Unconjugated (TMAB-00474) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining. 7. Paraformaldehyde-fixed, paraffin embedded Human Breast Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CPT1A Polyclonal Antibody, Unconjugated (TMAB-00474) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.        |
| Application | |
| Recommended Dose | ICC/IF=1:50-200; IF=1:100-500; IHC-Fr=1:100-500; IHC-P=1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Mitochondrion outer membrane; Multi-pass membrane protein. |
| Tissue Specificity | Strong expression in kidney and heart, and lower in liver and skeletal muscle. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | The mitochondrial oxidation of long-chain fatty acids is nitiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]. |
| Immunogen | KLH conjugated synthetic peptide: human CPT1A |
| Antigen Species | Human |
| Gene Name | CPT1A |
| Gene ID | |
| Protein Name | Carnitine O-palmitoyltransferase 1, liver isoform |
| Uniprot ID | |
| Biology Area | Metabolism of lipids and lipoproteins,Metabolism,Fatty acids,Lipid metabolism,Mitochondrial markers,Fatty acid oxidation,Obesity,Lipid metabolism,Mitochondrial,Mitochondria |
| Function | Catalyzes the transfer of the acyl group of long-chain fatty acid-CoA conjugates onto carnitine, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion. Plays an important role in triglyceride metabolism. |
| Molecular Weight | Theoretical: 86 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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