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Anti-PHPT1 Antibody (6V712)
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Catalog No. TMAY-02358
Alias PHP14, phosphohistidine phosphatase 1, HSPC141, HEL-S-132P, CGI-202
Anti-PHPT1 Antibody (6V712) is a Mouse antibody targeting PHPT1. Anti-PHPT1 Antibody (6V712) can be used in ELISA(Cap).
Anti-PHPT1 Antibody (6V712)
Anti-PHPT1 Antibody (6V712)
😃Good
Catalog No. TMAY-02358Alias PHP14, phosphohistidine phosphatase 1, HSPC141, HEL-S-132P, CGI-202
Anti-PHPT1 Antibody (6V712) is a Mouse antibody targeting PHPT1. Anti-PHPT1 Antibody (6V712) can be used in ELISA(Cap).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $69 | 7-10 days | |
| 100 μL | $199 | 7-10 days |
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Product Introduction
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Antigen Details
Chemical Properties
| Description | Anti-PHPT1 Antibody (6V712) is a Mouse antibody targeting PHPT1. Anti-PHPT1 Antibody (6V712) can be used in ELISA(Cap). |
| Alias | PHP14, phosphohistidine phosphatase 1, HSPC141, HEL-S-132P, CGI-202 |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 6V712 |
| Reactivity | Human |
| Application | ELISA(Cap) |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human PHPT1 (rh PHPT1; TMPY-02002; Q9NRX4-1; Ala2-Tyr125). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | PHPT1, also known as 14 kDa phosphohistidine phosphatase, phosphohistidine phosphatase 1, protein janus-A homolog, PHP14, is a cytoplasm protein which belongs to the janus family. PHPT1 / PHP14 is expressed abundantly in heart and skeletal muscle. Phosphatases are a diverse group of enzymes that regulate numerous cellular processes. Much of what is known relates to the tyrosine, threonine, and serine phosphatases, whereas the histidine phosphatases have not been studied as much. Protein histidine phosphorylation exists widely in vertebrates, and it plays important roles in signal transduction and other cellular functions. Protein histidine phosphorylation accounts for about 6% of the total protein phosphorylation in eukaryotic cells. The knowledge about eukaryotic PHPT (protein histidine phosphatase) is still very limited. To date, only one vertebrate PHPT has been discovered, and two crystal structures of human PHPT1 have been solved. PHPT1 / PHP14 can dephosphorylate a variety of proteins (e.g. ATP-citrate lyase and the beta-subunit of G proteins). A putative active site has been identified by its electrostatic character, ion binding, and conserved protein residues. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human PHPT1 Protein (TMPY-02002) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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