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Anti-Optineurin Antibody (3K110) is a Mouse antibody targeting Optineurin. Anti-Optineurin Antibody (3K110) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $198 | 7-10 days |
Description | Anti-Optineurin Antibody (3K110) is a Mouse antibody targeting Optineurin. Anti-Optineurin Antibody (3K110) can be used in ELISA. |
Alias | TFIIIA-INTP, optineurin, NRP, HYPL, HIP7, GLC1E, FIP2, ALS12 |
Ig Type | Monoclonal Mouse IgG2b |
Clone | 3K110 |
Reactivity | Human |
Application | ELISA |
Recommended Dose | ELISA: 1:1000-1:2000 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Optineurin / OPTN (rh Optineurin / OPTN; TMPY-03501; NP_068815.2; Met1-Ile577). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | OPTN (Optineurin) is a Protein Coding gene. The Optineurin gene encodes the coiled-coil containing protein optineurin. Optineurin is a multifunctional adaptor protein intimately involved in various vesicular trafficking pathways. Through interactions with an array of proteins, such as myosin VI, huntingtin, Rab8, and Tank-binding kinase 1, as well as via its oligomerization, optineurin can act as an adaptor, scaffold, or signal regulator to coordinate many cellular processes associated with the trafficking of membrane-delivered cargo. It is widely expressed in fat, adrenal, and other tissues. Certain mutations in OPTN (gene OPTN) are associated with primary open-angle glaucoma, a leading cause of irreversible blindness, and amyotrophic lateral sclerosis, a fatal motor neuron disease. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human Optineurin / OPTN Protein (TMPY-03501) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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