Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Spantide acetate is a selective antagonist of NK1 receptor with Kis of 230 nM and 8150 nM for NK1 and NK2.
Description | Spantide acetate is a selective antagonist of NK1 receptor with Kis of 230 nM and 8150 nM for NK1 and NK2. |
In vivo | In examined animals, Spantide acetate (50 nM and 100 nM) all causes a complete respiratory arrest[1]. In female C57BL/6 and BALB/c mice, Spantide acetate (36 μg; i.p.) significantly decreases the number of bacterial counts, perforated corneas, and PMNs. Spantide acetate downregulates the mRNA levels for type I cytokines IFN-γ, IL-6, TNF-α, MIP-2, and IL-1β[2]. |
Synonyms | Spantide acetate(91224-37-2 Free base) |
Molecular Weight | 1557.84 |
Formula | C77H112N20O15 |
CAS No. | T20413L |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 15.58 mg/mL (10 mM)
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Spantide acetate T20413L GPCR/G Protein Neuroscience Neurokinin receptor Spantide acetate(91224-37-2 Free base) Inhibitor inhibitor inhibit