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Spantide acetate
🥰Excellent
Catalog No. T20413L
Alias Spantide acetate(91224-37-2 Free base)
Spantide acetate is a selective antagonist of NK1 receptor with Kis of 230 nM and 8150 nM for NK1 and NK2.
Spantide acetate
🥰Excellent
Purity: 98.92%
Catalog No. T20413LAlias Spantide acetate(91224-37-2 Free base)
Spantide acetate is a selective antagonist of NK1 receptor with Kis of 230 nM and 8150 nM for NK1 and NK2.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $131 | In Stock | |
| 5 mg | $347 | In Stock | |
| 10 mg | $553 | In Stock | |
| 25 mg | $893 | In Stock | |
| 50 mg | $1,220 | In Stock | |
| 100 mg | $1,650 | In Stock | |
| 500 mg | $3,280 | In Stock |
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Purity:98.92%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Spantide acetate is a selective antagonist of NK1 receptor with Kis of 230 nM and 8150 nM for NK1 and NK2. |
| In vivo | In examined animals, Spantide acetate (50 nM and 100 nM) all causes a complete respiratory arrest[1]. In female C57BL/6 and BALB/c mice, Spantide acetate (36 μg; i.p.) significantly decreases the number of bacterial counts, perforated corneas, and PMNs. Spantide acetate downregulates the mRNA levels for type I cytokines IFN-γ, IL-6, TNF-α, MIP-2, and IL-1β[2]. |
| Alias | Spantide acetate(91224-37-2 Free base) |
| Molecular Weight | 1557.84 |
| Formula | C77H112N20O15 |
| Smiles | CC(C[C@H](NC([C@H](NC([C@@H](NC([C@H](NC([C@@H](NC([C@@H](NC([C@@H]1CCCN1C([C@H](CCCCN)NC([C@@H]2CCCN2C([C@H](N)CCCNC(N)=N)=O)=O)=O)=O)CCC(N)=O)=O)CCC(N)=O)=O)CC3=CNC4=CC=CC=C43)=O)CC5=CC=CC=C5)=O)CC6=CNC7=CC=CC=C76)=O)C(N[C@@H](C(N)=O)CC(C)C)=O)C.CC(O)=O |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
| Solubility Information | DMSO: 15.58 mg/mL (10 mM), Sonication is recommended.  | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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