Contact UsQuotation
Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty
Proceed to checkoutContinue shopping
TOPBioactivityChemical infoStorage&SolubilityCalculator

Pleconaril

🥰Excellent
Catalog No. T4536Cas No. 153168-05-9
Alias Win 63843, VP 63843, Picovir

Pleconaril (VP 63843) is a capsid inhibitor used previously to treat enterovirus infections. Pleconaril is effective in inhibiting replication (IC50: 50 nM).

Pleconaril

Pleconaril

🥰Excellent
Purity: 99.09%
Catalog No. T4536Alias Win 63843, VP 63843, PicovirCas No. 153168-05-9
Pleconaril (VP 63843) is a capsid inhibitor used previously to treat enterovirus infections. Pleconaril is effective in inhibiting replication (IC50: 50 nM).
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$32In StockIn Stock
2 mg$45In StockIn Stock
5 mg$68In StockIn Stock
10 mg$105In StockIn Stock
25 mg$223In StockIn Stock
50 mg$340In StockIn Stock
100 mg$493In StockIn Stock
200 mg$719In StockIn Stock
1 mL x 10 mM (in DMSO)$68In StockIn Stock
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
TargetMol
View More

Batch Information

Select Batch
Purity:99.09%
Contact us for more batch information

Resource Download

COA

Product Introduction

Bioactivity
Description
Pleconaril (VP 63843) is a capsid inhibitor used previously to treat enterovirus infections. Pleconaril is effective in inhibiting replication (IC50: 50 nM).
Targets&IC50
Capsid:50 nM
In vitro
Pleconaril is a capsid inhibitor designed to dock within a hydrophobic pocket formed by the capsid proteins VP1, VP3 and VP2. Pleconaril leads to stiffening of the capsid structure, preventing RNA release into the cell.
SynonymsWin 63843, VP 63843, Picovir
Chemical Properties
Molecular Weight381.35
FormulaC18H18F3N3O3
Cas No.153168-05-9
SmilesCc1cc(CCCOc2c(C)cc(cc2C)-c2noc(n2)C(F)(F)F)on1
Relative Density.1.271 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (131.11 mM), Heating is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (5.24 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.6223 mL13.1113 mL26.2226 mL131.1132 mL
5 mM0.5245 mL2.6223 mL5.2445 mL26.2226 mL
10 mM0.2622 mL1.3111 mL2.6223 mL13.1113 mL
20 mM0.1311 mL0.6556 mL1.3111 mL6.5557 mL
50 mM0.0524 mL0.2622 mL0.5245 mL2.6223 mL
100 mM0.0262 mL0.1311 mL0.2622 mL1.3111 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Win-63843Win63843VP-63843VP63843VirusProteaseVirus ProteaseRhinovirusPleconarilInhibitorinhibitHRVsHRVHEVsHEVEnterovirusAntiviral
Related Tags: buy Pleconaril | purchase Pleconaril | Pleconaril cost | order Pleconaril | Pleconaril chemical structure | Pleconaril in vitro | Pleconaril formula | Pleconaril molecular weight
TargetMol | Logo

Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.