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H-Val-Pro-Pro-OH

Name: H-Val-Pro-Pro-OH
Brand: TargetMol
SKU: T7354
Price: 34 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T7354Cas No. 58872-39-2

H-Val-Pro-Pro-OH is an inhibitor of Angiotensin I converting enzyme (ACE)( IC50 : 9 μM).

H-Val-Pro-Pro-OH

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Purity: 98.23%

Catalog No. T7354Cas No. 58872-39-2

H-Val-Pro-Pro-OH is an inhibitor of Angiotensin I converting enzyme (ACE)( IC50 : 9 μM).

Pack Size	Price	Availability
5 mg	$34	In Stock
10 mg	$53	In Stock
25 mg	$98	In Stock
50 mg	$143	In Stock
100 mg	$209	In Stock
200 mg	$313	In Stock

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Batch Information

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Purity:98.23%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	H-Val-Pro-Pro-OH is an inhibitor of Angiotensin I converting enzyme (ACE)( IC50 : 9 μM).
Targets&IC50	ACE:9 μM

Chemical Properties

Molecular Weight	311.38
Formula	C₁₅H₂₅N₃O₄
Cas No.	58872-39-2
Smiles	C(=O)([C@H]1N(C([C@H](C(C)C)N)=O)CCC1)N2[C@H](C(O)=O)CCC2
Relative Density.	1.274 g/cm3 (Predicted)
Sequence	H-Val-Pro-Pro-OH
Sequence Short	H-VPP-OH

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 10 mM, Sonication is recommended.

H2O: 20 mg/mL (64.23 mM), Sonication is recommended.

Solution Preparation Table

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	3.2115 mL	16.0576 mL	32.1151 mL	160.5755 mL
5 mM	0.6423 mL	3.2115 mL	6.4230 mL	32.1151 mL
10 mM	0.3212 mL	1.6058 mL	3.2115 mL	16.0576 mL

H2O

	1mg	5mg	10mg	50mg
20 mM	0.1606 mL	0.8029 mL	1.6058 mL	8.0288 mL
50 mM	0.0642 mL	0.3212 mL	0.6423 mL	3.2115 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc