Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-Phospho-GRIN1 (Ser890) Polyclonal Antibody (Synonyms: p-GRIN1 (Ser890), p-GRIN1 (S890), GRIN1 (p-Ser890)|...)

Catalog No. TMAC-02856 Copy Product Info
🥰Excellent
Anti-Phospho-GRIN1 (Ser890) Polyclonal Antibody is a Rabbit antibody targeting Phospho-GRIN1 (Ser890). Anti-Phospho-GRIN1 (Ser890) Polyclonal Antibody can be used in ICC/IF,IHC,WB.

Anti-Phospho-GRIN1 (Ser890) Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAC-02856
Synonyms p-GRIN1 (Ser890), p-GRIN1 (S890), GRIN1 (p-Ser890), GRIN1 (p-S890)

Anti-Phospho-GRIN1 (Ser890) Polyclonal Antibody is a Rabbit antibody targeting Phospho-GRIN1 (Ser890). Anti-Phospho-GRIN1 (Ser890) Polyclonal Antibody can be used in ICC/IF,IHC,WB.

Anti-Phospho-GRIN1
(Ser890) Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2187-10 days7-10 days
100 μL$3167-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
Add to Cart
Add to Quotation
For research use only—not for human use. No sales to individuals. Use as intended only.
Questions
TargetMol
View More

Product Introduction

Bioactivity
Description
Anti-Phospho-GRIN1 (Ser890) Polyclonal Antibody is a Rabbit antibody targeting Phospho-GRIN1 (Ser890). Anti-Phospho-GRIN1 (Ser890) Polyclonal Antibody can be used in ICC/IF,IHC,WB.
Synonymsp-GRIN1 (Ser890), p-GRIN1 (S890), GRIN1 (p-Ser890), GRIN1 (p-S890)
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of NMDAR1 (pS890) expression in A549 (A), U87MG (B) whole cell lysates.
2. Immunohistochemical analysis of NMDAR1 (pS890) staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system.
3. Immunofluorescent analysis of NMDAR1 (pS890) staining in A549 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4℃ in a hidified chamber. Cells were washed with PBST and incubated with a Alexa Fluor 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.
verifiedActivityverifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:500-1000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundNMDA receptors are members of the ionotropic class of glutamate receptors, which also includes Kainate and AMPA receptors. NMDA receptors consist of NR1 subunits combined with one or more NR2 (A-D) or NR3 (A-B) subunits. The ligand-gated channel is permeable to cations including Ca2+, and at resting membrane potentials NMDA receptors are inactive due to a voltage-dependent blockade of the channel pore by Mg2+. NMDA receptor activation, which requires binding of glutamate and glycine, leads to an influx of Ca2+ into the postsynaptic region where it activates several signaling cascades, including pathways leading to the induction of long-term potentiation (LTP) and depression (LTD). NMDA receptors have a critical role in excitatory synaptic transmission and plasticity in the CNS. They govern a range of physiological conditions including neurological disorders caused by excitotoxic neuronal injury, psychiatric disorders and neuropathic pain syndromes.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of serine890(A-S-S(p)-F-K) derived from Human NMDAR1
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 105 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Calculator

  • Dilution Calculator
  • Reconstitution Calculator

Keywords

Related Tags: buy Anti-Phospho-GRIN1 (Ser890) Polyclonal Antibody | purchase Anti-Phospho-GRIN1 (Ser890) Polyclonal Antibody | Anti-Phospho-GRIN1 (Ser890) Polyclonal Antibody cost | order Anti-Phospho-GRIN1 (Ser890) Polyclonal Antibody | Anti-Phospho-GRIN1 (Ser890) Polyclonal Antibody molecular weight