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Anti-Urocortin-3 Polyclonal Antibody

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Catalog No. TMAB-01938
Alias Urocortin-3, Urocortin III (Ucn III), UCN3, Stresscopin, SPC

Anti-Urocortin-3 Polyclonal Antibody is a Rabbit antibody targeting Urocortin-3. Anti-Urocortin-3 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.

Anti-Urocortin-3 Polyclonal Antibody

Anti-Urocortin-3 Polyclonal Antibody

😃Good
Catalog No. TMAB-01938Alias Urocortin-3, Urocortin III (Ucn III), UCN3, Stresscopin, SPC
Anti-Urocortin-3 Polyclonal Antibody is a Rabbit antibody targeting Urocortin-3. Anti-Urocortin-3 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
Pack SizePriceAvailabilityQuantity
50 μL$2227-10 days
100 μL$3747-10 days
200 μL$5277-10 days
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Product Introduction

Bioactivity
Description
Anti-Urocortin-3 Polyclonal Antibody is a Rabbit antibody targeting Urocortin-3. Anti-Urocortin-3 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
SynonymsUrocortin-3, Urocortin III (Ucn III), UCN3, Stresscopin, SPC
Ig Type
IgG
Reactivity
Rat (predicted:Human,Mouse,Pig,Cow,Horse,Rabbit)
Verified Activity
Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (Urocortin 3) Polyclonal Antibody, Unconjugated (TMAB-01938) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructionsand DAB staining.
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1 mg/mL
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human UCN3
Antigen Species
Human
Gene Name
UCN3
Gene ID
Protein Name
Urocortin-3
Uniprot ID
Biology Area
Response to hypoxia,Ischemia / Reperfusion,Blood,Hypoxia,Cancer,Heart disease,Neurotrophins,Metabolism,Hormones
Function
Urocortin 3 is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally related to the corticotropin-releasing factor (CRF) gene and the encoded product is an endogenous ligand for CRF type 2 receptors. In the brain it may be responsible for the effects of stress on appetite. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin II. A powerful cytoprotective effect of urocortin peptide administration against ischemia and reperfusion injury has been demonstrated in isolated cardiomyocyte models, as well as in the intact heart both in vitro and in vivo.
Chemical Properties
Molecular WeightTheoretical: 4/18 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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