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Tris(3-hydroxypropyltriazolylmethyl)amine

Name: Tris(3-hydroxypropyltriazolylmethyl)amine
Brand: TargetMol
SKU: TXB-00017
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TXB-00017Cas No. 760952-88-3

Alias THPTA

Tris(3-hydroxypropyltriazolylmethyl)amine (THPTA) serves as an effective accelerator ligand for copper-catalysed azide-alkyne coupling (CuAAC), concurrently reducing toxicity to cells or organisms.

Tris(3-hydroxypropyltriazolylmethyl)amine

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Purity: 98.365%

Catalog No. TXB-00017Alias THPTACas No. 760952-88-3

Tris(3-hydroxypropyltriazolylmethyl)amine (THPTA) serves as an effective accelerator ligand for copper-catalysed azide-alkyne coupling (CuAAC), concurrently reducing toxicity to cells or organisms.

Pack Size	Price	Availability
50 mg	$30	In Stock
100 mg	$40	In Stock
200 mg	$56	In Stock

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Purity:98.365%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Tris(3-hydroxypropyltriazolylmethyl)amine (THPTA) serves as an effective accelerator ligand for copper-catalysed azide-alkyne coupling (CuAAC), concurrently reducing toxicity to cells or organisms.
In vitro	Tris(3-hydroxypropyltriazolylmethyl)amine (250 μM, 1-5 minutes) as a ligand to accelerate the CuAAC reaction significantly improved the rate and efficiency of the CuAAC reaction, while protecting cells from oxidative damage. [1]
Synonyms	THPTA

Chemical Properties

Molecular Weight	434.5
Formula	C₁₈H₃₀N₁₀O₃
Cas No.	760952-88-3
Smiles	OCCCN1N=NC(CN(CC2=CN(CCCO)N=N2)CC3=CN(CCCO)N=N3)=C1
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: ≥ 130 mg/mL, Sonication is recommended.

DMSO: 80.00 mg/mL (184.12 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3015 mL	11.5075 mL	23.0150 mL	115.0748 mL
5 mM	0.4603 mL	2.3015 mL	4.6030 mL	23.0150 mL
10 mM	0.2301 mL	1.1507 mL	2.3015 mL	11.5075 mL
20 mM	0.1151 mL	0.5754 mL	1.1507 mL	5.7537 mL
50 mM	0.0460 mL	0.2301 mL	0.4603 mL	2.3015 mL
100 mM	0.0230 mL	0.1151 mL	0.2301 mL	1.1507 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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