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Mal-amido-PEG2-TFP ester is a polyethylene glycol (PEG)-based linker featuring amide functionality and a trifluorophenyl (TFP) ester group, used in PROTAC synthesis as a PEG-based PROTAC linker [1].
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | $30 | Backorder |
Description | Mal-amido-PEG2-TFP ester is a polyethylene glycol (PEG)-based linker featuring amide functionality and a trifluorophenyl (TFP) ester group, used in PROTAC synthesis as a PEG-based PROTAC linker [1]. |
In vitro | PROTACs consist of two distinct ligands linked together: one binds to an E3 ubiquitin ligase, and the other targets a specific protein. These compounds harness the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 476.38 |
Formula | C20H20F4N2O7 |
Cas No. | 1431291-44-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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