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PLP (139-151)

Name: PLP (139-151)
Brand: TargetMol
SKU: TP1282
Rating: 4.5 (1 reviews)

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Catalog No. TP1282Cas No. 131334-43-5

Alias PLP 139-151

PLP (139-151) is an amino acid fragment from positions 139 to 151 of myelin proteolipid protein (PLP), which is used to induce the relapsing-remitting experimental autoimmune encephalomyelitis (RR-EAE) model.

PLP (139-151)

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Catalog No. TP1282Alias PLP 139-151Cas No. 131334-43-5

Pack Size	Price	Availability	Quantity
1 mg	$85	Backorder
5 mg	$355	Backorder

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Product Introduction

Bioactivity

Description	PLP (139-151) is an amino acid fragment from positions 139 to 151 of myelin proteolipid protein (PLP), which is used to induce the relapsing-remitting experimental autoimmune encephalomyelitis (RR-EAE) model.
Synonyms	PLP 139-151

Chemical Properties

Molecular Weight	1537.79
Formula	C₇₂H₁₀₄N₂₀O₁₆S
Cas No.	131334-43-5
Relative Density.	1.332 g/cm3 (Predicted)

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 50 mg/mL (32.51 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	0.6503 mL	3.2514 mL	6.5028 mL	32.5142 mL
5 mM	0.1301 mL	0.6503 mL	1.3006 mL	6.5028 mL
10 mM	0.0650 mL	0.3251 mL	0.6503 mL	3.2514 mL
20 mM	0.0325 mL	0.1626 mL	0.3251 mL	1.6257 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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