EGF Protein, Human, Recombinant (His)

Name: EGF Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPS-00023
Price: 38 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: Urogastrone, URG, epidermal growth factor) Copy Product Info

Synonyms: Urogastrone, URG, epidermal growth factor

Catalog No. TMPS-00023 Copy Product Info

EGF Protein, Human, Recombinant (His) is expressed in E. coli. The accession number is P01133.

Pack Size	Price	USA Stock	Global Stock
5 µg	$38	-	In Stock
10 µg	$57	-	In Stock
20 µg	$87	-	In Stock
50 µg	$158	7-10 days	7-10 days
100 µg	$239	-	In Stock
200 µg	$383	7-10 days	7-10 days
500 µg	$689	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:> 95% as determined by SDS-PAGE

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	ED 50 < 0.2 ng/ml, as determined by a cell proliferation assay using Balb/c 3T3 cells, corresponding to a specific activity of ≥ 5.0 × 10 6 units/mg.
Description	EGF Protein, Human, Recombinant (His) is expressed in E. coli. The accession number is P01133.
Species	Human
Expression System	E. coli
Tag	His
Accession Number	P01133
Construction	Asn971-Arg1023
Protein Purity	> 95% as determined by SDS-PAGE
Endotoxin	< 0.2 EU/μg of protein as determined by the LAL method.
Formulation	Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	Urogastrone, URG, epidermal growth factor
Research Background	Epidermal Growth Factor (EGF) is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells. Additionally, EGF has been shown to inhibit gastric secretion, and to be involved in wound healing. EGF signals through the EGF receptor (EGFR) also known as erbB1, is a class I tyrosine kinase receptor. This receptor also binds with TGF-α and VGF (vaccinia virus growth factor). EGF-receptor binding results in cellular proliferation, differentiation, and survival. EGF is a low-molecular-weight polypeptide first purified from the mouse submandibular gland, but since then found in many human tissues including submandibular gland, parotid gland. Salivary EGF, which seems also regulated by dietary inorganic iodine, also plays an important physiological role in the maintenance of oro-esophageal and gastric tissue integrity. The biological effects of salivary EGF include healing of oral and gastroesophageal ulcers, inhibition of gastric acid secretion, stimulation of DNA synthesis as well as mucosal protection from intraluminal injurious factors such as gastric acid, bile acids, pepsin, and trypsin and to physical, chemical and bacterial agents.

Chemical Properties

Molecular Weight

~7.2 kDa (Reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.