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Anti-DUSP1 Antibody (8I5)
😃Good
Catalog No. TMAB-00576
Alias VH1, VH 1, Serine/threonine specific protein phosphatase, Ptpn16, PTPN10, PTPN 10, Protein tyrosine phosphatase CL100, MKP-1, MKP1, Mitogen activated protein kinase phosphatase 1, MAP kinase phosphatase 1, HVH1, HVH 1, EC 3.1.3.48, EC 3.1.3.16, DUSP-1, Dual specificity protein phosphatase hVH1, Dual specificity protein phosphatase 1, Dual Specificity Phosphatase 1, CL100, CL 100, 3ch134
Anti-DUSP1 Antibody (8I5) is a Rabbit antibody targeting DUSP1. Anti-DUSP1 Antibody (8I5) can be used in FCM,IF,IHC-Fr,IHC-P,WB.
Anti-DUSP1 Antibody (8I5)
Anti-DUSP1 Antibody (8I5)
😃Good
Catalog No. TMAB-00576Alias VH1, VH 1, Serine/threonine specific protein phosphatase, Ptpn16, PTPN10, PTPN 10, Protein tyrosine phosphatase CL100, MKP-1, MKP1, Mitogen activated protein kinase phosphatase 1, MAP kinase phosphatase 1, HVH1, HVH 1, EC 3.1.3.48, EC 3.1.3.16, DUSP-1, Dual specificity protein phosphatase hVH1, Dual specificity protein phosphatase 1, Dual Specificity Phosphatase 1, CL100, CL 100, 3ch134
Anti-DUSP1 Antibody (8I5) is a Rabbit antibody targeting DUSP1. Anti-DUSP1 Antibody (8I5) can be used in FCM,IF,IHC-Fr,IHC-P,WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $272 | 7-10 days | |
| 100 μL | $488 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-DUSP1 Antibody (8I5) is a Rabbit antibody targeting DUSP1. Anti-DUSP1 Antibody (8I5) can be used in FCM,IF,IHC-Fr,IHC-P,WB. |
| Synonyms | VH1, VH 1, Serine/threonine specific protein phosphatase, Ptpn16, PTPN10, PTPN 10, Protein tyrosine phosphatase CL100, MKP-1, MKP1, Mitogen activated protein kinase phosphatase 1, MAP kinase phosphatase 1, HVH1, HVH 1, EC 3.1.3.48, EC 3.1.3.16, DUSP-1, Dual specificity protein phosphatase hVH1, Dual specificity protein phosphatase 1, Dual Specificity Phosphatase 1, CL100, CL 100, 3ch134 |
| Ig Type | IgG |
| Clone | 8I5 |
| Reactivity | (predicted:Human,Mouse,Rat) |
| Application | |
| Recommended Dose | WB: 1:500-1000; IHC-P: 1:100-500; IHC-Fr: 1:50-200; IF: 1:100-500; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Tissue Specificity | Expressed at high levels in the lung, liver placenta and pancreas. Moderate levels seen in the heart and skeletal muscle. Lower levels found in the brain and kidney. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues. |
| Immunogen | A synthesized peptide: human DUSP1 |
| Antigen Species | Human |
| Gene Name | DUSP1 |
| Gene ID | |
| Protein Name | Dual specificity protein phosphatase 1 |
| Uniprot ID | |
| Biology Area | Ser / Thr Phosphatases,Tyrosine Phosphatases |
| Function | Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185'. |
| Molecular Weight | Theoretical: 39 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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