CD39 Protein, Mouse, Recombinant (His)

Name: CD39 Protein, Mouse, Recombinant (His)
Brand: TargetMol
SKU: TMPY-02808
Price: 43 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: NTPDase-1, ectonucleoside triphosphate diphosphohydrolase 1, Cd39, AA408691, 2610206B08Rik) Copy Product Info

Synonyms: NTPDase-1, ectonucleoside triphosphate diphosphohydrolase 1, Cd39, AA408691, 2610206B08Rik

Catalog No. TMPY-02808 Copy Product Info

Purity: 97%

CD39 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 51 kDa and the accession number is P55772.

Pack Size	Price	USA Stock	Global Stock
5 µg	$43	-	In Stock
10 µg	$65	-	In Stock
20 µg	$98	7-10 days	7-10 days
50 µg	$200	-	In Stock
100 µg	$355	7-10 days	7-10 days
200 µg	$629	7-10 days	7-10 days
500 µg	$1,330	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:97%

Appearance:Solution

Color:Transparent

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Measured by its ability to hydrolyze the 5’phosphategroups from the substrate adenosine 5’triphosphate(ATP). The specific activity is > 25,000 pmoles/min/μg.
Description	CD39 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 51 kDa and the accession number is P55772.
Species	Mouse
Expression System	Baculovirus Insect Cells
Tag	C-His
Accession Number	P55772
Construction	A DNA sequence encoding the mouse ENTPD1 (P55772) extracellular domain (Thr 38-Ile 478) was fused with a polyhistidine tag at the C-terminus and a signal peptide at the N-terminus. Predicted N terminal: Thr 38
Protein Purity	> 95 % as determined by SDS-PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Supplied as sterile 20 mM Tris, 500 mM NaCl, pH 7.4, 10% gly.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Synonyms	NTPDase-1, ectonucleoside triphosphate diphosphohydrolase 1, Cd39, AA408691, 2610206B08Rik
Research Background	CD39, also known as ENTPD1, belongs to the GDA1/CD39 NTPase family. It is expressed primarily on activated lymphoid cells and can also be detected in endothelial tissues. The vascular isoform and the placental isoform II are present in both placenta and umbilical vein, whereas placental isoform I is present in placenta only. CD39 can hydrolyze both nucleoside triphosphates and diphosphates. It is the dominant ecto nucleotidase of vascular and placental trophoblastic tissues and appears to modulate the functional expression of type 2 purinergic (P2) G protein coupled receptors (GPCRs). CD39 transgenic mice exhibit impaired platelet aggregation, prolonged bleeding times, and resistance to systemic thromboembolism. There is a correlation between ATP hydrolysis and triglycerides in patients with chronic heart disease, suggesting a relationship between ATP diphosphohydrolase and thrombogenesis. In the nervous system, CD39 could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission.

Chemical Properties

Molecular Weight

51 kDa (predicted)

Storage & Solubility Information

Shipping	Proteins are shipped with blue ice.
Storage	It is recommended to store the product under sterile conditions at -20°C to -80°C. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.