Shopping Cart
- Remove All
- Your shopping cart is currently empty
O-Demethyl apremilast is an active metabolite of the phosphodiesterase 4 (PDE4) inhibitor apremilast .1It inhibits the activity of PDE4 isolated from U937 cells and LPS-induced TNF-α production in isolated human peripheral blood mononuclear cells (PBMCs; IC50s = 8.3 and 5.6 μM, respectively). O-Demethyl apremilast is also an oxidative degradation product of apremilast.2,3
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | TBD | 35 days | |
10 mg | TBD | 35 days | |
25 mg | TBD | 35 days |
Description | O-Demethyl apremilast is an active metabolite of the phosphodiesterase 4 (PDE4) inhibitor apremilast .1It inhibits the activity of PDE4 isolated from U937 cells and LPS-induced TNF-α production in isolated human peripheral blood mononuclear cells (PBMCs; IC50s = 8.3 and 5.6 μM, respectively). O-Demethyl apremilast is also an oxidative degradation product of apremilast.2,3 |
Molecular Weight | 446.47 |
Formula | C21H22N2O7S |
Cas No. | 1384441-38-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO:PBS (pH 7.2) (1:2): 0.3 mg/mL (0.67 mM), Sonication is recommended. DMSO: 30 mg/mL (67.19 mM), Sonication is recommended. DMF: 30 mg/mL (67.19 mM), Sonication is recommended. |
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.